In the realm of fine chemicals and specialized intermediates, understanding the fundamental characteristics and applications of each compound is vital for professionals in chemistry, pharmaceuticals, and materials science. 6-Bromo-4-hydroxyquinoline, identified by the CAS number 145369-94-4, is one such compound that serves as a critical building block in various synthetic processes.

Chemical Identity and Structure
6-Bromo-4-hydroxyquinoline is an organic compound characterized by a quinoline ring system that has been substituted with a bromine atom at the 6-position and a hydroxyl group at the 4-position. This specific arrangement of functional groups imparts unique reactivity, making it a sought-after intermediate in organic synthesis. Its molecular formula is C9H6BrNO, and its molecular weight is approximately 224.06 g/mol. Often supplied as a powder, its physical appearance can range from tan to white or light yellow, depending on its purity and manufacturing process.

Key Physical and Chemical Properties
The compound exhibits a high melting point, typically cited around 283°C. This elevated melting point suggests a stable crystalline structure. In terms of solubility, it is generally described as slightly soluble in chloroform and methanol, common organic solvents used in laboratory procedures. These properties are crucial for chemists when designing reaction conditions, purification methods, and handling protocols. The presence of the bromine atom makes it amenable to various palladium-catalyzed cross-coupling reactions, while the hydroxyl group can undergo derivatization, such as esterification or etherification.

Applications in Research and Industry
The primary utility of 6-Bromo-4-hydroxyquinoline lies in its role as an intermediate for synthesizing more complex organic molecules. In the pharmaceutical industry, it is frequently used as a precursor for developing novel drug candidates, as the quinoline scaffold is a common motif in many biologically active compounds. Researchers may utilize it in the synthesis of potential therapeutic agents for various diseases. Beyond pharmaceuticals, it can also find applications in materials science or as a building block for specialized chemicals.

For procurement managers and researchers looking to buy 6-Bromo-4-hydroxyquinoline, it is essential to source from reliable manufacturers and suppliers. Ensuring high purity, typically above 98.0%, is crucial for successful synthesis outcomes. When inquiring about purchasing this compound, always confirm the CAS number (145369-94-4) and request detailed product specifications and a Certificate of Analysis (CoA). Investigating suppliers, particularly those with a strong presence in the fine chemical market, can provide access to quality materials and valuable technical support, facilitating smoother R&D operations.