For procurement managers and R&D scientists in the pharmaceutical industry, sourcing high-quality chemical intermediates is paramount to successful drug development. One such critical intermediate is 6-Bromo-4-hydroxyquinoline, identified by its CAS number 145369-94-4. Understanding its properties, applications, and the best ways to purchase it is key to efficient operations.

Understanding 6-Bromo-4-hydroxyquinoline
6-Bromo-4-hydroxyquinoline is a heterocyclic organic compound, frequently utilized as a building block in sophisticated organic synthesis. Its chemical structure makes it a valuable precursor for a range of more complex molecules, particularly in the pharmaceutical sector. Typically appearing as a tan or white to light yellow powder, it exhibits a high melting point, usually around 283°C. Its solubility in solvents like chloroform and methanol facilitates its use in various reaction conditions.

Key Applications in Pharmaceuticals and Research
The primary utility of 6-Bromo-4-hydroxyquinoline lies in its role as an intermediate for synthesizing Active Pharmaceutical Ingredients (APIs). Its quinoline core structure, functionalized with a bromine atom and a hydroxyl group, provides strategic points for further chemical modifications. Researchers often seek this compound for developing new therapeutic agents, exploring its potential in creating novel compounds with desired biological activities.

For procurement managers, identifying a reliable supplier is crucial. When looking to buy 6-Bromo-4-hydroxyquinoline, prioritizing manufacturers who can guarantee high purity (often exceeding 98.0% by GC) is essential. The consistency of such intermediates directly impacts the yield and quality of the final product. Therefore, understanding the specifications and quality control measures of a potential supplier is a non-negotiable step.

Finding Reliable Manufacturers and Suppliers in China
China has emerged as a global hub for chemical manufacturing, offering a wide array of intermediates like 6-Bromo-4-hydroxyquinoline. When sourcing from Chinese manufacturers, it is advisable to look for companies that have a strong track record in producing fine chemicals and pharmaceutical intermediates. Key factors to consider include:

  • Product Purity and Specifications: Ensure they provide detailed Certificates of Analysis (CoA) confirming purity and relevant physical properties.
  • Production Capacity and Scalability: For projects requiring larger quantities, verifying the supplier's capacity to scale up production is important.
  • Regulatory Compliance and Quality Systems: Look for suppliers adhering to international quality standards, which can be a sign of reliability.
  • Customer Service and Technical Support: A responsive supplier offering technical assistance can be invaluable.

When you need to purchase 6-Bromo-4-hydroxyquinoline, engaging with reputable manufacturers and suppliers ensures you obtain a product that meets your exacting standards. Exploring options from established Chinese chemical companies can often provide a balance of high quality and competitive pricing, making it an attractive proposition for your research and development procurement needs.

For those in the market to buy this crucial intermediate, focusing on suppliers who can provide consistent quality and reliable service will ultimately contribute to the success of your projects. Investigate manufacturers who clearly list their CAS number, purity, and offer responsive inquiry channels to secure your supply of 6-Bromo-4-hydroxyquinoline.