In the dynamic world of chemical synthesis, having access to reliable and high-quality intermediates is crucial for the success of research and manufacturing endeavors. 1-Chloro-2-iodobenzene (CAS 615-41-8) is a prime example of such a vital compound, widely utilized across various sectors due to its unique chemical properties. For procurement professionals and researchers alike, understanding how to effectively source this chemical is a key aspect of operational efficiency. This guide provides comprehensive insights for buyers looking to buy 1-chloro-2-iodobenzene.

Understanding 1-Chloro-2-iodobenzene: Properties and Identification

1-Chloro-2-iodobenzene, identified by its CAS number 615-41-8, is an aromatic compound distinguished by the presence of both a chlorine atom and an iodine atom attached to a benzene ring at adjacent positions. This structural feature dictates its reactivity profile.

  • Chemical Formula: C6H4ClI
  • Appearance: Commonly described as a light yellow liquid, its visual consistency can be an initial indicator of purity.
  • Purity: For most applications in synthesis and pharmaceutical development, a high purity level, typically ≥99%, is essential. This ensures minimal interference from impurities and consistent reaction outcomes.
  • Boiling Point: With a boiling point of 234-235°C, it possesses good thermal stability for typical synthetic procedures.
  • Density: Approximately 1.952 g/mL at 25°C, which is relevant for handling and volume calculations.

Always ensure your chosen supplier provides a detailed Certificate of Analysis (CoA) to confirm these specifications.

Key Applications Driving Demand

The demand for 1-Chloro-2-iodobenzene is driven by its broad utility in synthetic chemistry:

  • Organic Synthesis Intermediate: It acts as a fundamental building block, particularly in metal-catalyzed cross-coupling reactions. The iodine atom's propensity for oxidative addition with palladium catalysts makes it ideal for forming new carbon-carbon bonds, essential for creating complex organic structures. This is a cornerstone of modern synthetic chemistry, supporting the development of novel materials, pharmaceuticals, and agrochemicals.
  • Pharmaceutical Industry: This compound is a critical precursor in the synthesis of numerous Active Pharmaceutical Ingredients (APIs) and advanced drug candidates. Its structure allows for regioselective functionalization, which is paramount in designing molecules with specific biological activities. Researchers often seek 1-chloro-2-iodobenzene for sale to facilitate their drug discovery programs.
  • Research and Development: Academic and industrial research labs frequently employ 1-Chloro-2-iodobenzene to explore new synthetic routes, develop novel catalysts, or synthesize specialized compounds for various scientific investigations.

The ability to source this intermediate from a reliable manufacturer significantly impacts the speed and success of R&D projects.

Strategic Sourcing: Tips for Buyers

When procuring chemicals like 1-Chloro-2-iodobenzene, a strategic approach is vital:

  • Supplier Vetting: Prioritize suppliers with a proven track record, strong quality control systems, and excellent customer service. Companies offering comprehensive documentation like CoAs are highly recommended.
  • Purity Verification: Always confirm the minimum purity required for your application. For most advanced synthetic needs, ≥99% is the benchmark.
  • Price Competitiveness: Compare 1-chloro-2-iodobenzene price from multiple suppliers, especially those based in manufacturing hubs like China, to secure the best value. Direct sourcing from manufacturers often yields cost savings.
  • Sample Testing: Before committing to bulk orders, obtaining and testing samples ensures the product meets your specific quality and performance expectations.
  • Logistics and Packaging: Discuss packaging requirements and shipping options to ensure the chemical arrives safely and efficiently, in compliance with relevant regulations.

As a leading 1-chloro-2-iodobenzene supplier and manufacturer, NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing high-quality intermediates to support your synthesis needs. We understand the importance of reliability and consistency in the chemical supply chain. Contact us today to discuss your requirements and obtain a competitive quote.