Diethyl Pyrocarbonate (DEPC) is a versatile chemical reagent with crucial applications in two distinct yet vital areas of biological research: RNA preservation and protein modification. Its ability to function effectively as an RNase inhibitor makes it a standard component in protocols for RNA isolation, ensuring that these delicate nucleic acid molecules remain intact and usable for downstream analyses such as gene expression studies. Simultaneously, its reactivity with specific amino acid residues allows for targeted chemical modifications in proteins, providing valuable insights into their structure and function. As a leading chemical manufacturer, we are dedicated to providing high-quality DEPC that supports both these critical applications.

In the realm of RNA biology, the ubiquitous presence of RNases poses a constant threat to RNA integrity. DEPC acts by carbamoylating the active sites of RNases, effectively neutralizing their enzymatic activity. This makes the preparation of DEPC-treated water and the subsequent treatment of labware and reagents a non-negotiable step for researchers working with RNA. The efficacy of DEPC in creating an RNase-free environment is well-established, and laboratories worldwide rely on this reagent to achieve consistent and reproducible results. For those looking to purchase DEPC, selecting a supplier known for purity and reliability is key.

Furthermore, DEPC's utility extends to protein chemistry. It specifically reacts with the imidazole ring of histidine residues and, to a lesser extent, with tyrosine residues. This chemical modification can be used to study the role of these residues in protein function, to inhibit enzyme activity, or to introduce labels for detection purposes. The precision with which DEPC can interact with these amino acids makes it a valuable tool for biochemists and structural biologists. Our commitment as a supplier in China is to ensure that researchers have access to this high-quality reagent to advance their work in both RNA biology and protein science. Whether you are isolating RNA or characterizing proteins, DEPC is a reagent that offers significant benefits.