Cosmetic Active Ingredients

Acetyl Tetrapeptide-15

CAS No.928007-64-1
GradeIndustrial / Pharmaceutical
Availability● In Stock

Acetyl Tetrapeptide-15 is a bioactive cosmetic peptide clinically proven to soothe neurosensitive skin by modulating inflammatory responses and enhancing skin tolerance.

Request a Quote & Full COA

Product Technical Details

Product Overview

Acetyl Tetrapeptide-15 is a cutting-edge cosmetic active ingredient specifically engineered for the management of hypersensitive and reactive skin conditions. Marketed under the trade name Skinasensyl™, this tetrapeptide functions through a neurocosmetic mechanism by targeting cutaneous nerve endings to reduce discomfort and irritation. Its molecular structure—N-Acetyl-L-tyrosyl-L-prolyl-L-phenylalanyl-L-phenylalaninamide—enables precise interaction with skin receptors involved in pain and inflammation signaling pathways.

Specifications

Molecular Formula	C₃₄H₃₉N₅O₆
Molecular Weight	613.70 g/mol
Density	1.3 ± 0.1 g/cm³
Boiling Point	1055.3 ± 65.0 °C at 760 mmHg
Flash Point	592.0 ± 34.3 °C
Vapour Pressure	0.0 ± 0.3 mmHg at 25°C
Refractive Index	1.617
Appearance	White Lyophilized Powder
Assay (Purity)	≥95.0%

Industrial Applications

This peptide is widely incorporated into premium dermocosmetic formulations designed for sensitive, intolerant, or post-procedure skin. Key benefits include:

Significant reduction in stinging, burning, and itching sensations
Downregulation of pro-inflammatory mediators such as substance P and CGRP
Enhancement of skin barrier resilience and sensory tolerance
Suitable for leave-on products including serums, creams, and lotions at typical use levels of 0.001–0.01%

Manufacturers seeking high-efficacy alternatives for soothing actives can leverage Acetyl Tetrapeptide-15 as a scientifically validated, drop-in solution that meets global regulatory standards for cosmetic ingredients.