Cosmetic Active Ingredients

Dipeptide-2

  • CAS No.24587-37-9
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

Dipeptide-2 is a bioactive cosmetic ingredient clinically shown to reduce under-eye puffiness and dark circles by inhibiting ACE activity and enhancing microcirculation.

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Product Technical Details

Product Overview

Dipeptide-2 (CAS 24587-37-9) is a synthetically derived dipeptide composed of L-valine and L-tryptophan, widely recognized in the cosmetic industry for its targeted efficacy in periorbital skincare formulations. As a potent angiotensin-converting enzyme (ACE) inhibitor, Dipeptide-2 helps modulate local vascular tone around the delicate eye area, thereby improving microcirculation and reducing fluid accumulation that leads to edema and discoloration.

Specifications

Molecular FormulaC₁₆H₂₁N₃O₃
Molecular Weight303.36 g/mol
AppearanceWhite powder
Assay≥98.0%
Density1.3 ± 0.1 g/cm³
Boiling Point604.8 ± 55.0 °C at 760 mmHg
Flash Point319.6 ± 31.5 °C
Vapour Pressure0.0 ± 1.8 mmHg at 25°C
Refractive Index1.624
StorageStore in a cool, dry, and well-ventilated area
Packaging5 kg/drum; custom packaging available upon request

Industrial Applications

Dipeptide-2 is exclusively formulated for advanced cosmetic applications, particularly in premium eye care products designed to address signs of fatigue and aging. Its mechanism of action—through selective ACE inhibition—supports dermal vascular health without systemic effects, making it ideal for topical use. Key benefits include:

  • Reduction of under-eye puffiness by minimizing localized fluid retention
  • Visible lightening of dark circles through enhanced capillary circulation
  • Compatibility with sensitive skin formulations due to its biomimetic peptide structure
  • Stability in aqueous and emulsion-based delivery systems

As a high-value active ingredient, Dipeptide-2 is suitable for inclusion in serums, creams, and gels targeting the periocular zone, offering formulators a scientifically backed solution for visible rejuvenation.