Cosmetic Active Ingredients

Diprotin A

  • CAS No.90614-48-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

Diprotin A is a bioactive tripeptide and selective DPP IV inhibitor used in advanced cosmetic formulations for skin rejuvenation and barrier support.

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Product Technical Details

Product Overview

Diprotin A (L-Isoleucyl-L-prolyl-L-isoleucine) is a naturally derived tripeptide renowned for its potent inhibitory activity against dipeptidyl peptidase IV (DPP IV). This enzyme plays a critical role in the degradation of bioactive peptides involved in skin homeostasis and repair. As a high-purity cosmetic active ingredient, Diprotin A supports dermal integrity, enhances microcirculation, and promotes the retention of key signaling molecules that contribute to youthful, resilient skin.

Specifications

Molecular FormulaC₁₇H₃₁N₃O₄
Molecular Weight341.45 g/mol
AppearanceWhite to off-white powder
Assay≥98.0%
Density1.14 g/cm³
Boiling Point583.1°C at 760 mmHg
Flash Point306.5°C
Refractive Index1.517

Industrial Applications

In the field of cosmeceuticals, Diprotin A is leveraged as a functional active due to its ability to modulate enzymatic pathways linked to skin aging. By inhibiting DPP IV, it helps preserve endogenous peptides such as stromal cell-derived factor-1 (SDF-1), which supports the homing of regenerative cells to stressed or damaged tissue. This mechanism translates into improved skin texture, enhanced barrier function, and reduced appearance of fine lines.

  • Stabilizes key dermal signaling peptides
  • Supports microvascular health in epidermal layers
  • Compatible with aqueous and emulsion-based delivery systems
  • Suitable for anti-aging, restorative, and sensitive-skin formulations

Stored in a cool, dry, and well-ventilated environment, Diprotin A maintains stability under standard cosmetic manufacturing conditions. Supplied in 25 kg drums or customized packaging upon request, it meets stringent quality standards for global regulatory compliance.