Cosmetic Active Ingredients

Laminin-1 Peptide

  • CAS No.131167-89-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity Laminin-1 peptide (IKVAV) designed for advanced cosmetic formulations and biomaterial surface modification to enhance cell adhesion and skin repair.

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Product Technical Details

Product Overview

The Laminin-1 peptide, widely recognized by its core sequence IKVAV, represents a cutting-edge bioactive ingredient designed for high-performance cosmetic and biomedical applications. This specific pentapeptide, chemically defined as L-Isoleucyl-L-lysyl-L-valyl-L-alanyl-L-valine, is derived from the laminin protein structure known for its critical role in cell biology. Our manufacturing process ensures exceptional purity levels, making it an ideal choice for formulators seeking to enhance product efficacy through scientifically validated mechanisms. As a key component in modern skincare science, this peptide facilitates crucial biological interactions that support tissue integrity and regeneration.

Mechanism of Action

The biological efficacy of this peptide stems from its ability to mimic the cell-binding domain of laminin-1. Upon application, the IKVAV sequence interacts specifically with cell surface integrins, triggering signaling pathways that promote adhesion and migration. This interaction is vital for maintaining the structural coherence of epithelial tissues. In cosmetic formulations, this mechanism translates to improved skin barrier function and accelerated recovery from environmental stressors. The peptide acts as a molecular bridge, encouraging cells to anchor firmly within the extracellular matrix, which is essential for maintaining youthful skin architecture and resilience against aging factors.

Industrial Applications

Primarily utilized in the development of advanced skincare products, this ingredient is highly valued for its regenerative properties. It is frequently incorporated into serums, creams, and masks aimed at anti-aging, wound healing, and skin revitalization. Beyond cosmetics, the peptide serves a significant role in biomaterials science, where it is used to modify surface properties of medical devices to improve biocompatibility. Researchers also employ this compound in cell culture applications to stimulate neural stem cell attachment and growth. Its versatility allows for integration into diverse matrices without compromising stability or activity.

Key Advantages

  • Enhances cell adhesion and proliferation effectively
  • Supports skin barrier repair and regeneration processes
  • High stability in various cosmetic formulation systems
  • Validated performance in biomaterial surface modification
  • Consistent quality backed by rigorous analytical testing

Technical Specifications

ParameterSpecification
CAS Number131167-89-0
Molecular FormulaC25H48N6O6
Molecular Weight528.685
AppearanceWhite to off-white powder
Purity (Assay)≥95.0%
Density1.1±0.1 g/cm3
Storage ConditionCool, ventilated place

Quality Assurance and Handling

Every batch of our Laminin-1 peptide undergoes strict quality control protocols to ensure compliance with international standards. We utilize high-performance liquid chromatography (HPLC) and mass spectrometry to verify identity and purity. The product is packaged in secure containers, typically 25 kg drums, though custom packaging solutions are available to meet specific client logistics requirements. Proper storage in a cool and ventilated environment is recommended to maintain optimal stability over time. We provide comprehensive documentation, including Certificates of Analysis (COA), to support regulatory submissions and quality assurance audits for our global manufacturing partners.