Intermediates

2-Butyl-3-(3,5-Diiodo-4-Hydroxybenzoyl)Benzofuran

  • CAS No.1951-26-4
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity pharmaceutical intermediate for Amiodarone synthesis. Reliable supply with full COA and strict quality control.

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Product Technical Details

Product Overview

2-Butyl-3-(3,5-Diiodo-4-Hydroxybenzoyl)Benzofuran is a specialized pharmaceutical intermediate critical for the production of cardiovascular therapeutic agents. As a key precursor in the synthesis of Amiodarone Hydrochloride, this compound plays an essential role in the manufacturing pipeline for medications targeting arrhythmias and related cardiac conditions. Our facility produces this chemical under stringent quality management systems to ensure consistency and reliability for downstream API manufacturers.

We understand the critical nature of supply chain stability in the pharmaceutical industry. Therefore, we maintain robust inventory levels and adhere to rigorous testing protocols. Each batch undergoes comprehensive analysis to verify structural integrity and purity profiles, ensuring seamless integration into your synthesis processes. Our commitment to excellence supports global pharmaceutical partners in maintaining their production schedules and regulatory compliance.

Technical Specifications

ParameterSpecification
CAS Number1951-26-4
Molecular FormulaC19H16I2O3
Molecular Weight546.14 g/mol
AppearanceOff-white crystalline powder
Assay98.0% - 102.0%
Melting Point142-144ºC
Loss on Drying≤0.5%
Single Impurity≤0.25%
Total Impurities≤0.5%
Storage ConditionRefrigerator (2-8ºC)

Industrial Applications

This compound serves primarily as a building block in the multi-step synthesis of Amiodarone Hydrochloride. It is utilized by pharmaceutical manufacturers to construct the core benzofuran structure required for the final active pharmaceutical ingredient. The high iodine content and specific substitution pattern make it indispensable for achieving the desired pharmacological profile in the final medication.

Beyond its primary use, this intermediate is valuable for research and development teams exploring novel analogues within the benzofuran chemical space. Our production capabilities support both large-scale commercial manufacturing and smaller-scale R&D requirements. We offer flexible packaging solutions to accommodate various production volumes while maintaining product integrity during transit.

Quality Assurance and Packaging

Quality is paramount in our operations. We provide a Certificate of Analysis (COA) with every shipment, detailing all critical quality attributes tested against internal and pharmacopoeial standards. Our packaging consists of 25kg drums lined with protective materials to prevent moisture ingress and contamination. Custom packaging configurations are available upon request to meet specific logistical or handling requirements.

We recommend storing this material in a cool, dry, and well-ventilated area away from direct sunlight. Proper handling procedures should be followed to maintain stability. Our technical support team is available to assist with storage guidelines and safety data information. Partner with us for a reliable source of high-quality pharmaceutical intermediates designed to meet the demanding standards of the global healthcare industry.