3-Bromo-5-fluoro-2-methoxypyridine
- CAS-Nr.884494-81-9
- QualitätIndustrie / Pharma
- Verfügbarkeit● Auf Lager
High-purity 3-Bromo-5-fluoro-2-methoxypyridine (CAS 884494-81-9) designed for advanced pharmaceutical synthesis. Reliable supply with strict quality control for global research and production needs.
Angebot anfordernTechnische Produktdetails
Product Overview
3-Bromo-5-fluoro-2-methoxypyridine is a highly specialized heterocyclic building block extensively utilized in modern medicinal chemistry and organic synthesis. This compound features a unique substitution pattern on the pyridine ring, incorporating both bromo and fluoro functionalities alongside a methoxy group. These structural elements make it an invaluable precursor for the development of complex pharmaceutical agents and agrochemical products. Our manufacturing facility ensures that every batch meets rigorous international standards, providing researchers and industrial partners with a reliable source of high-quality chemical intermediates.
The presence of the bromine atom at the third position facilitates various cross-coupling reactions, such as Suzuki-Miyaura or Buchwald-Hartwig couplings, which are critical steps in constructing biaryl structures found in many active pharmaceutical ingredients. Meanwhile, the fluoro substituent enhances metabolic stability and bioavailability in final drug candidates. This combination of reactivity and stability makes the compound a strategic choice for process chemistry teams aiming to optimize synthesis routes.
Technical Specifications
We maintain strict quality control protocols throughout the production process to guarantee consistency and purity. The physical and chemical properties listed below are verified through advanced analytical techniques including HPLC, NMR, and GC-MS. Customers can expect comprehensive documentation with every shipment to support regulatory compliance and internal quality audits.
| Parameter | Value |
|---|---|
| CAS Number | 884494-81-9 |
| Molecular Formula | C6H5BrFNO |
| Molecular Weight | 206.01 g/mol |
| Purity | ≥98.0% |
| Appearance | White to off-white powder |
| Boiling Point | 188.4±35.0 °C at 760 mmHg |
| Density | 1.6±0.1 g/cm3 |
| Flash Point | 67.7±25.9 °C |
Industrial Applications
This pyridine derivative serves as a key intermediate in the synthesis of various therapeutic compounds. Its primary application lies in the pharmaceutical sector, where it is used to introduce specific heterocyclic motifs into drug molecules. The versatility of the molecule allows it to participate in nucleophilic substitution reactions as well as metal-catalyzed transformations. Additionally, it is employed in the research and development of new chemical entities where precise structural modification is required.
- Medicinal chemistry research and drug discovery programs
- Process development for scalable pharmaceutical manufacturing
- Custom synthesis of complex organic molecules
- Agrochemical intermediate production
- Material science applications requiring functionalized pyridines
Quality Assurance and Storage
To preserve the integrity of the chemical structure, proper storage conditions are essential. The product should be kept in a tightly closed container to prevent exposure to moisture and air, which could potentially degrade quality over time. We recommend storing the material in a cool, dry, and well-ventilated area away from incompatible substances. Our quality assurance team provides a Certificate of Analysis (COA) for every batch, confirming that all specifications meet the agreed-upon standards. Global shipping options are available to ensure timely delivery to laboratories and production facilities worldwide.
