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3-(Trifluoromethoxy)aniline

  • CAS-Nr.1535-73-5
  • QualitätIndustrie / Pharma
  • Verfügbarkeit● Auf Lager

High-purity 3-(Trifluoromethoxy)aniline (CAS 1535-73-5) is a premium fluorinated intermediate designed for complex organic synthesis and pharmaceutical research applications.

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Technische Produktdetails

Product Overview

3-(Trifluoromethoxy)aniline is a specialized fluorinated aromatic amine that serves as a critical building block in modern organic chemistry. Characterized by the presence of a trifluoromethoxy group at the meta position of the aniline ring, this compound offers unique electronic and steric properties that enhance the metabolic stability and lipophilicity of downstream molecules. Our facility produces this chemical intermediate under strict quality control standards to ensure consistency for large-scale industrial applications.

As a leading global manufacturer, we understand the demanding requirements of pharmaceutical and agrochemical research. The introduction of fluorine atoms into organic structures is a key strategy in medicinal chemistry to improve binding affinity and bioavailability. This product provides a reliable source of fluorinated functionality for researchers and process chemists developing next-generation therapeutic agents and crop protection solutions.

Key Specifications

ParameterSpecification
Chemical Name3-(Trifluoromethoxy)aniline
CAS Number1535-73-5
Molecular FormulaC7H6F3NO
Molecular Weight177.12 g/mol
Purity (GC)≥99.0%
AppearanceColourless to yellow to orange clear liquid
Density1.325 g/cm3
Boiling Point72-73°C
Refractive Index1.466

Industrial Applications

This fluorinated aniline derivative is primarily utilized as a versatile intermediate in the synthesis of complex organic compounds. Its primary applications span across several high-value sectors including pharmaceuticals, agrochemicals, and advanced materials. In the pharmaceutical industry, it is employed in the preparation of various active pharmaceutical ingredients (APIs) where the trifluoromethoxy moiety contributes to enhanced pharmacokinetic properties.

Furthermore, the compound is valuable in agrochemical research for developing novel herbicides and pesticides. The chemical stability of the ether linkage allows for robust performance in diverse environmental conditions. Process chemists also value this material for its reactivity profile, which facilitates efficient coupling reactions and functional group transformations during multi-step synthesis routes.

Quality Assurance and Packaging

We maintain a rigorous quality management system to guarantee the integrity of every batch. Each production lot undergoes comprehensive analysis using gas chromatography (GC) and other advanced analytical techniques to verify purity levels and identify impurities. A Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Standard packaging consists of 200 kg drums, ensuring safe and efficient transport for bulk orders. However, we offer flexible packaging solutions tailored to specific customer requirements, including smaller quantities for laboratory-scale research. Our logistics team ensures timely delivery while maintaining compliance with international shipping regulations for chemical substances.

Storage and Handling

To maintain optimal quality, 3-(Trifluoromethoxy)aniline should be stored in a cool, well-ventilated area away from direct sunlight and heat sources. The container must be kept tightly closed when not in use to prevent moisture absorption and oxidation. Personnel handling this material should adhere to standard safety protocols, including the use of appropriate personal protective equipment (PPE) such as gloves and safety goggles. For detailed safety information, please refer to the Safety Data Sheet (SDS) provided upon request.