2-Nitro-4-(Trifluoromethyl)Aniline Bulk Price Per Kg 2026
- Market Stability: 2026 forecasts indicate stable pricing for CAS 400-98-6 due to optimized fluorination processes.
- Technical Specs: Standard industrial purity reaches 98% with a melting point range of 105°C to 109°C.
- Supply Chain: Bulk procurement requires verified global manufacturer partnerships for consistent lot-to-lot quality.
The pharmaceutical and agrochemical sectors rely heavily on specialized fluorinated intermediates to enhance metabolic stability and bioavailability in final active ingredients. Among these, 2-Nitro-4-(trifluoromethyl)aniline (CAS: 400-98-6) stands out as a critical building block for synthesizing high-performance pesticides and medicinal compounds. As we approach 2026, procurement managers are increasingly focused on securing long-term supply contracts that guarantee both cost efficiency and rigorous quality control. Understanding the technical nuances of this chemical is essential for negotiating effective bulk price agreements.
At NINGBO INNO PHARMCHEM CO.,LTD., we recognize that price is only one component of value. True cost-effectiveness in fine chemical procurement derives from consistent reaction yields, reliable logistics, and adherence to strict safety standards. This analysis provides a comprehensive overview of the market dynamics, technical specifications, and synthesis considerations necessary for informed purchasing decisions in the coming fiscal year.
Technical Specifications and Quality Standards
When evaluating suppliers for fluorinated aniline derivatives, technical data sheets must be scrutinized against industry benchmarks. The physical properties of the material directly impact downstream processing, particularly in reduction and coupling reactions. Standard commercial grades typically target a minimum purity of 98%, ensuring minimal interference in subsequent synthetic steps.
| Parameter | Specification |
|---|---|
| Chemical Name | 2-Nitro-4-(trifluoromethyl)aniline |
| CAS Number | 400-98-6 |
| Molecular Formula | C7H5F3N2O2 |
| Formula Weight | 206.13 g/mol |
| Purity (GC/HPLC) | ≥ 98.0% |
| Melting Point | 105°C to 109°C |
| Hazard Class | 6.1 (Toxic) |
Maintaining the correct melting point range is a primary indicator of industrial purity. Deviations below 105°C often suggest the presence of unreacted starting materials or isomeric impurities, which can catalyze side reactions during scale-up. Our quality assurance protocols ensure that every batch meets these thermal specifications before release.
Synthesis Routes and Manufacturing Efficiency
The commercial viability of this intermediate depends heavily on the efficiency of the synthesis route employed. Common manufacturing pathways involve the nitration of 4-(trifluoromethyl)aniline or the reduction of corresponding dinitro compounds. Each method presents distinct advantages regarding yield and waste management.
Direct nitration strategies must carefully control temperature and acid concentration to prevent over-nitration or oxidation of the amino group. Conversely, reduction routes require precise catalyst selection to avoid dehalogenation of the trifluoromethyl group. Advanced manufacturing facilities utilize continuous flow chemistry to enhance safety and improve selectivity, resulting in higher overall yields and reduced solvent consumption.
For buyers assessing technical compatibility, it is crucial to verify the impurity profile. When sourcing high-purity 3-Nitro-alpha derivatives, buyers should request detailed chromatograms to confirm the absence of regioisomers. This level of transparency is standard practice for a reliable global manufacturer committed to supporting complex synthetic workflows.
2026 Market Price Trends and Volume Discounts
Forecasting the bulk price per kilogram for 2026 requires an analysis of raw material costs, particularly fluorine sources and nitration agents. While spot prices may fluctuate due to energy costs and regulatory changes, long-term contract pricing offers stability. Manufacturers who integrate vertically—producing their own trifluoromethyl precursors—can offer more competitive rates.
Volume discount structures typically tier based on metric ton commitments. Procurement strategies should account for lead times, as custom synthesis batches may require 4 to 6 weeks for production and quality testing. Establishing a partnership with NINGBO INNO PHARMCHEM CO.,LTD. allows clients to lock in pricing frameworks that protect against market volatility while ensuring priority allocation during peak demand periods.
Key Factors Influencing Cost
- Raw Material Availability: Fluctuations in the cost of trifluorotoluene derivatives directly impact final pricing.
- Environmental Compliance: Adherence to strict waste disposal regulations adds to operational costs but ensures supply continuity.
- Packaging and Logistics: Hazard Class 6.1 materials require specialized packaging and documented transport, influencing FOB terms.
Safety, Handling, and Regulatory Compliance
Safety data sheets (SDS) classify this compound as toxic upon ingestion, skin contact, or inhalation. Proper handling procedures mandate the use of personal protective equipment (PPE), including chemical-resistant gloves and respiratory protection. Storage should be maintained at ambient temperatures in a cool, dry, and well-ventilated area, segregated from oxidizing agents.
Regulatory compliance extends beyond safety to include documentation such as Certificates of Analysis (COA) and Method Validation Reports. For international shipments, proper classification under UN2811 is mandatory. Ensuring that your supplier provides comprehensive documentation minimizes customs delays and ensures adherence to local chemical inventory laws.
Conclusion: Securing Supply for Future Production
As the demand for fluorinated pharmaceuticals and agrochemicals grows, the reliability of your intermediate supply chain becomes a critical competitive advantage. The market for 3-Nitro-4-aminobenzotrifluoride is evolving, with a clear shift towards suppliers who can demonstrate technical expertise alongside commercial flexibility.
By prioritizing industrial purity and establishing transparent communication channels with your chemical partner, you can mitigate production risks. For organizations seeking a dependable source for CAS 400-98-6, engaging with a dedicated manufacturer ensures that quality specifications are met consistently. Contact our technical sales team today to discuss volume requirements and secure your supply chain for 2026 and beyond.