Industrial Purity Dibenzo[B,D]Furan-3-Ylboronic Acid Coa and Manufacturing Specifications
- High-Purity Specifications: Guaranteed minimum 99% purity with comprehensive COA documentation including HPLC and NMR data.
- Optimized Synthesis: Advanced lithiation-borylation processes ensure consistent yields and minimal halogenated impurities.
- Global Bulk Supply: Scalable manufacturing capacity for OLED intermediates with strict inert gas storage protocols.
In the landscape of advanced organic electronics and pharmaceutical development, the reliability of key intermediates is paramount. Dibenzo[b,d]furan-3-ylboronic acid (CAS: 395087-89-5) serves as a critical building block for constructing complex heterocyclic systems. As a premier global manufacturer, NINGBO INNO PHARMCHEM CO.,LTD. specializes in delivering this compound with the rigorous industrial purity required for high-performance OLED materials and fine chemical synthesis. This technical overview details the manufacturing standards, quality assurance protocols, and procurement specifications necessary for bulk industrial buyers.
Technical Specifications and Physicochemical Properties
Understanding the precise physicochemical profile of the material is essential for process integration. The compound, often referenced in technical literature as B-3-dibenzofuranylboronic acid, exhibits specific stability characteristics that must be managed during storage and handling. The following table outlines the critical data points verified during our quality control batches.
| Property | Specification |
|---|---|
| Product Name | Dibenzo[b,d]furan-3-ylboronic acid |
| CAS Number | 395087-89-5 |
| Molecular Formula | C12H9BO3 |
| Molecular Weight | 212.01 g/mol |
| Appearance | White to off-white solid |
| Purity (HPLC) | ≥ 99.0% |
| Storage Conditions | Under inert gas (Nitrogen/Argon) at 2-8°C |
| HS Code | 2931900090 |
Manufacturing Process and Synthesis Route Optimization
The production of high-grade boronic acids requires meticulous control over the reaction environment to prevent protodeboronation and oxidative degradation. The preferred synthesis route involves the lithiation of a brominated dibenzofuran precursor followed by quenching with a borate ester. Maintaining anhydrous conditions and strict temperature control during the addition of n-butyllithium is critical to maximizing yield.
Industrial scale-up often faces challenges regarding heat dissipation and mixing efficiency. Our manufacturing process utilizes optimized reactor configurations to ensure uniform reaction kinetics. Post-reaction, the crude product undergoes acidic hydrolysis and rigorous purification steps. This ensures that residual halides and metal catalysts are reduced to ppm levels, a requirement for materials destined for electronic applications. When sourcing high-purity Dibenzo[b,d]furan-3-ylboronic acid, buyers should verify that the supplier employs these advanced purification techniques to guarantee batch-to-batch consistency.
Quality Assurance and COA Documentation
For B2B transactions, the Certificate of Analysis (COA) is the definitive document verifying product integrity. A comprehensive COA for this intermediate must include more than just a purity percentage. It should detail the results of orthogonal analytical methods. We employ High-Performance Liquid Chromatography (HPLC) for quantitative purity assessment and Nuclear Magnetic Resonance (NMR) spectroscopy for structural confirmation.
Key impurities monitored include the starting bromide, homocoupling byproducts, and phenol derivatives resulting from oxidation. Our quality assurance team ensures that every batch released meets the stringent specifications required for downstream coupling reactions, such as Suzuki-Miyaura cross-couplings. This level of scrutiny supports our clients in maintaining their own production yields and minimizing waste.
Applications as an OLED Building Block
The primary commercial application for this compound is as an OLED building block. The dibenzofuran core provides excellent thermal stability and high triplet energy levels, making it ideal for host materials in phosphorescent OLED devices. The boronic acid functionality allows for versatile functionalization, enabling chemists to construct complex conjugated systems with precise electronic properties.
Beyond electronics, the compound serves as a valuable intermediate in pharmaceutical organic synthesis. Its stability under various reaction conditions allows it to be used in the construction of biologically active molecules where the dibenzofuran scaffold imparts specific binding affinities. The demand for this material continues to grow as next-generation display technologies require increasingly pure and specialized chemical inputs.
Bulk Procurement and Safety Handling
Procuring chemicals for industrial use involves balancing cost with reliability. While spot market bulk price fluctuations occur, securing a long-term supply agreement with a verified manufacturer ensures stability. We offer scalable packaging solutions ranging from kilograms for R&D to metric tons for commercial production, all shipped with appropriate hazard documentation.
Safety is a critical component of handling boronic acids. According to GHS standards, the material carries hazard statements regarding ingestion, skin irritation, and respiratory irritation. Proper personal protective equipment (PPE), including gloves and eye protection, must be worn. Storage under inert gas is not merely a recommendation for purity but a safety measure to prevent the formation of potentially unstable peroxides upon prolonged exposure to air. NINGBO INNO PHARMCHEM CO.,LTD. adheres to strict international safety standards throughout the packaging and logistics process to ensure the material arrives safely at your facility.
Conclusion
The selection of a chemical partner is as critical as the selection of the material itself. By prioritizing industrial purity, robust analytical verification, and transparent manufacturing processes, we support the innovation goals of our global partners. Whether for large-scale OLED production or specialized pharmaceutical research, our commitment to quality ensures that your synthesis pathways remain efficient and reliable.