N,N,N-Triethylethanaminiumfluoriddihydrat Global Manufacturer Supplier: Technical & Commercial Overview
- NINGBO INNO PHARMCHEM CO.,LTD. supplies Tetraethylammonium fluoride dihydrate with ≥98% industrial purity and full COA documentation.
- Bulk price competitiveness driven by optimized synthesis route and in-house fluorination capabilities.
- Global export-ready logistics with flexible packaging options and MOQs tailored to B2B procurement needs.
Tetraethylammonium fluoride dihydrate (CAS 665-46-3), also known by its systematic IUPAC name N,N,N-Triethylethanaminiumfluoriddihydrat, is a critical phase-transfer catalyst widely used in organic synthesis, particularly in nucleophilic fluorination reactions and desilylation protocols. Its utility stems from the synergistic combination of a quaternary ammonium cation and a highly reactive fluoride anion, stabilized in a dihydrate crystalline matrix that enhances handling safety without compromising reactivity.
For industrial buyers evaluating global suppliers, technical consistency and supply chain reliability are non-negotiable. The compound—often abbreviated as TEAF—is typically produced via a two-step synthesis route: first, the quaternization of triethylamine with ethyl halide to form tetraethylammonium halide, followed by anion exchange using a soluble fluoride source such as potassium fluoride or hydrofluoric acid under controlled aqueous conditions. This process must be meticulously managed to avoid hydrolysis or decomposition, which directly impacts final industrial purity.
When sourcing high-purity Tetraethylammonium fluoride dihydrate, buyers should prioritize manufacturers with vertically integrated production capabilities and rigorous quality control. NINGBO INNO PHARMCHEM CO.,LTD. has established itself as a premier global manufacturer by implementing a refined synthesis route that minimizes residual halides and water variability, consistently delivering product with ≥98% assay by titration and ion chromatography.
Technical Specifications and Quality Assurance
Industrial-grade TEAF must meet stringent analytical benchmarks to perform reliably in sensitive synthetic transformations. Key parameters include fluoride content, water content (theoretical 12.7% for dihydrate), residual solvents, and heavy metals. Every batch from NINGBO INNO PHARMCHEM CO.,LTD. is accompanied by a comprehensive Certificate of Analysis (COA), detailing:
- Assay (by acid-base titration): ≥98.0%
- Fluoride ion content: 10.8–11.2% (theoretical: 11.0%)
- Water (Karl Fischer): 12.0–13.5%
- Residual chloride/bromide: <50 ppm
- Heavy metals (as Pb): <10 ppm
This level of analytical transparency ensures seamless integration into GMP-compliant workflows and reduces batch-to-batch variability—a common pain point when procuring from less-documented sources.
Bulk Pricing Dynamics and Supply Chain Efficiency
The bulk price of Tetraethylammonium fluoride dihydrate is influenced by raw material costs (particularly ethylating agents and fluoride salts), energy-intensive drying steps, and regulatory compliance for fluorine-containing compounds. NINGBO INNO PHARMCHEM CO.,LTD. mitigates cost volatility through strategic raw material partnerships and energy-efficient crystallization protocols, enabling competitive pricing even at multi-hundred-kilogram scales.
Unlike fragmented suppliers with limited scale, this manufacturer offers tiered pricing based on annual volume commitments, with typical minimum order quantities (MOQs) starting at 1 kg for sampling and scaling to 500+ kg for contract manufacturing. Lead times average 2–4 weeks post-order confirmation, supported by pre-certified export documentation (REACH, TSCA, ISO 9001).
Custom Packaging and Global Logistics
To address diverse handling requirements, NINGBO INNO PHARMCHEM CO.,LTD. provides multiple packaging configurations:
| Package Type | Net Weight | Material | Moisture Protection |
|---|---|---|---|
| Lab Scale | 100 g – 1 kg | HDPE bottle with PTFE-lined cap | Vacuum-sealed with desiccant |
| Intermediate Bulk | 5 – 25 kg | Multi-layer aluminum foil bag inside fiber drum | Nitrogen-purged, heat-sealed |
| Industrial Bulk | 50 – 500 kg | UN-certified HDPE drum with inner liner | Double-sealed under dry N₂ atmosphere |
All shipments comply with IMDG/IATA regulations for Class 8 corrosive substances (due to fluoride reactivity), and the company supports FOB, CIF, and DDP terms to over 60 countries. This end-to-end control—from manufacturing process to last-mile delivery—reduces risk of moisture uptake or contamination during transit, a frequent cause of performance failure in hygroscopic salts like TEAF.
Why Partner with NINGBO INNO PHARMCHEM CO.,LTD.?
As a top-tier global manufacturer of specialty quaternary ammonium salts, NINGBO INNO PHARMCHEM CO.,LTD. combines deep synthetic expertise with agile commercial operations. Their facility features dedicated fluorination suites, real-time moisture monitoring, and a QC lab accredited to ISO/IEC 17025 standards. This infrastructure ensures not only consistent industrial purity but also rapid response to custom requests—such as anhydrous TEAF variants or isotopically labeled derivatives.
For procurement teams seeking a reliable, audit-ready supplier of N,N,N-Triethylethanaminiumfluoriddihydrat, partnering with NINGBO INNO PHARMCHEM CO.,LTD. eliminates the guesswork associated with offshore sourcing. With transparent bulk price structures, validated synthesis route documentation, and full regulatory support, they deliver both chemical excellence and supply chain confidence.