Technical Specifications and Supply Chain Analysis for CAS 85013-98-5
- Kinetic Profile: Optimized synthesis routes ensure high yield consistency for complex fluorinated building blocks.
- Sourcing Stability: Direct factory engagement secures tonnage quantities and competitive bulk price structures.
- Audit Readiness: Full regulatory documentation including TSCA listing and batch-specific COA verification.
In the landscape of modern pharmaceutical intermediates, precise chemical characterization is paramount for scaling production. 4'-(Trifluoromethoxy)acetophenone, known systematically as 1-[4-(trifluoromethoxy)phenyl]ethanone, represents a critical fluorinated building block used in the development of agrochemicals and active pharmaceutical ingredients (APIs). As a premier global manufacturer, NINGBO INNO PHARMCHEM CO.,LTD. maintains rigorous control over the manufacturing process to ensure that every batch meets stringent industrial purity standards required for downstream synthesis.
Interpreting Certificate Of Analysis For Density And Purity
For process chemists and quality assurance teams, validating the physical constants of an aromatic ketone is the first step in vendor qualification. The molecular weight of 204.15 g/mol and the specific density of 1.278 g/cm³ are critical parameters that influence reaction stoichiometry and solvent selection. Deviations in these values often indicate the presence of isomeric impurities or residual solvents that can compromise subsequent reaction steps.
When evaluating potential partners, buyers must scrutinize the COA for refractive index data (ND20: 1.4550) and boiling point specifications (47-49°C at 15 torr). These physical specs serve as a fingerprint for chemical identity. At NINGBO INNO PHARMCHEM CO.,LTD., our quality control laboratories utilize high-resolution NMR and GC-MS to verify these parameters, ensuring that the material performs predictably in scale-up scenarios.
Key Physical and Chemical Parameters
| Parameter | Specification | Test Method |
|---|---|---|
| CAS Number | 85013-98-5 | Registry |
| Molecular Formula | C9H7F3O2 | Calculated |
| Molecular Weight | 204.15 g/mol | MS |
| Boiling Point | 47-49°C / 15 torr | Distillation |
| Density | 1.278 g/cm³ | Pychnometer |
| Refractive Index (ND20) | 1.4550 | Refractometer |
| Purity Grade | >98.0% (GC) | Gas Chromatography |
Verifying Physical Specs Against Competitor Catalog Data
Market intelligence suggests variability in the synthesis route employed by different facilities, which can lead to distinct impurity profiles. Some production methods may leave behind halogenated byproducts or unreacted phenols that are difficult to remove without specialized distillation columns. Procurement officers should demand batch-specific data rather than relying on generic catalog specifications.
Reliable sourcing involves more than just checking a box; it requires understanding the stable supply chain dynamics. Fluctuations in bulk price often correlate with raw material availability for fluorination reagents. By partnering directly with a manufacturer capable of custom synthesis and large-scale production, companies can mitigate the risk of supply chain disruptions that plague secondary distributors.
Batch Consistency Guarantees From Certified Fluorochemical Supplier
For executives overseeing operational risk, regulatory compliance is non-negotiable. This compound is TSCA listed, facilitating importation into key markets without additional pre-manufacture notices. However, maintaining this status requires consistent adherence to environmental and safety protocols, including proper handling of irritants (H317, H319).
Ensuring batch-to-batch consistency is essential for maintaining regulatory filings for downstream products. When sourcing high-purity 4-(Trifluoromethoxy)acetophenone, buyers should prioritize suppliers who offer full traceability from raw material intake to final dispatch. This level of transparency supports both R&D efficiency and commercial viability.
To secure a reliable partnership for your fluorination projects, we invite you to contact our technical sales team for a batch-specific COA, SDS, or bulk pricing quote.