4-Amino-5-Chloro-2,1,3-Benzothiadiazole Bulk Price Global Manufacturer Supply
- [Reaction Kinetics]: Optimized chlorination pathways ensure consistent yields and minimal byproduct formation for complex organic synthesis.
- [Procurement Stability]: Direct factory access guarantees tonnage quantities with verified batch-to-batch consistency and transparent costing.
- [Audit Readiness]: Full regulatory documentation packages including COA, SDS, and COO available to support global compliance standards.
In the competitive landscape of fine chemical manufacturing, securing a stable supply chain for critical heterocyclic intermediates is paramount. 4-Amino-5-chloro-2,1,3-benzothiadiazole (CAS: 115398-34-0) represents a high-value building block utilized across pharmaceutical and agrochemical sectors. As demand scales for downstream derivatives, procurement leaders and technical directors require a partner capable of delivering industrial purity alongside commercial viability. NINGBO INNO PHARMCHEM CO.,LTD. stands as a premier global manufacturer, offering robust production capabilities tailored to meet rigorous international standards.
Technical Synthesis and Impurity Profile
For process chemists and R&D teams, understanding the manufacturing backbone of this compound is essential for method validation. The production typically involves the selective chlorination of amino-substituted benzothiadiazole precursors. Achieving high selectivity is critical to minimize the formation of di-chlorinated byproducts or isomeric impurities that can complicate downstream coupling reactions.
Our manufacturing process utilizes a refined synthesis route designed to maximize conversion efficiency while maintaining a sharp melting point profile. Technical data indicates a standard melting point around 89°C, with a formula weight of 185.63. In alternative nomenclature, this compound is often referred to as 5-Chloro-benzo[1,2,5]thiadiazol-4-ylamine. Controlling the reaction temperature and stoichiometry during the halogenation step is vital to ensuring the final crystalline powder meets the required ≥97.0% purity threshold, though higher customization is available for sensitive applications.
Key Quality Parameters
To assist in technical evaluation, the following table outlines the standard physical and chemical specifications expected for commercial grade supply:
| Parameter | Specification | Test Method |
|---|---|---|
| Chemical Name | 4-Amino-5-chloro-2,1,3-benzothiadiazole | GC-MS / NMR |
| CAS Number | 115398-34-0 | N/A |
| Molecular Weight | 185.63 g/mol | Calculated |
| Purity (HPLC/GC) | ≥ 97.0% (Customizable to ≥99%) | Area Normalization |
| Melting Point | 88°C - 90°C | DSC / Capillary |
| Physical Form | Crystalline Powder | Visual / Microscopy |
| Appearance | Off-white to Light Yellow | Visual |
Procurement Strategy and Bulk Pricing Dynamics
For procurement officers, the bulk price of specialized intermediates is influenced by raw material availability, energy costs, and logistical complexity. Sourcing from a global manufacturer with integrated production facilities eliminates middleman markups and reduces lead time variability. When evaluating suppliers, it is crucial to verify the consistency of supply across multiple batches to prevent production stoppages in your own facility.
When sourcing high-purity 4-Amino-5-chloro-1,2,3-benzothiadiazole, buyers should prioritize vendors who provide immediate access to quality documentation. Unlike standard catalog suppliers, dedicated manufacturing partners like NINGBO INNO PHARMCHEM CO.,LTD. can generate batch-specific COA (Certificate of Analysis) documents upon request, ensuring that the material matches the technical requirements before shipment.
Commercial Viability and Regulatory Compliance
From an executive perspective, the integration of this chemical into broader product lines must align with regulatory frameworks. This compound serves as a vital pharmaceutical building block, notably acting as a Tizanidine intermediate in the synthesis of muscle relaxants. Consequently, the supply chain must adhere to strict quality management systems.
Scalability is another critical factor. Whether the requirement is for pilot plant trials or full-scale commercial production, the manufacturer must demonstrate the capacity to scale without compromising purity profiles. Furthermore, export compliance regarding customs documentation and Certificates of Origin (COO) must be streamlined to avoid delays at international ports. Our facility ensures that all shipments are accompanied by comprehensive Safety Data Sheets (SDS) and relevant trade documentation to facilitate smooth customs clearance.
Secure Your Supply Chain Today
Reliable access to fine chemicals requires a partnership built on transparency and technical expertise. To ensure your production lines remain operational with high-quality inputs, we invite you to contact our technical sales team for a batch-specific COA, SDS, or bulk pricing quote. Let us demonstrate how our optimized production capabilities can support your long-term strategic goals.