4-[5-(4-Pentyloxyphenyl)Isoxazol-3-Yl]Benzoic Acid Bulk Price Manufacturer 2026
- High Purity Standards: Supplying CAS 179162-55-1 with >98% to >99% HPLC purity for industrial applications.
- Scalable Production: Capabilities range from gram-scale research to multi-ton commercial manufacturing.
- Competitive Pricing: Optimized bulk price structures for long-term pharmaceutical supply contracts.
In the landscape of modern pharmaceutical development, securing reliable sources for complex organic intermediates is critical for maintaining production schedules and cost efficiency. 4-[5-(4-Pentyloxyphenyl)isoxazol-3-yl]benzoic acid (CAS: 179162-55-1) represents a vital structural component in the synthesis of advanced antifungal agents. As we approach 2026, demand for this specific Isoxazole benzoic acid derivative is projected to rise, driven by the expanding production of echinocandin-class medications. Procurement managers and process chemists must evaluate suppliers not only on cost but on technical capability, regulatory compliance, and supply chain stability.
At NINGBO INNO PHARMCHEM CO.,LTD., we specialize in the large-scale production of high-value pharmaceutical building blocks. Our manufacturing processes are designed to ensure consistent industrial purity levels that meet stringent global specifications. This article provides a technical and commercial analysis of sourcing this compound, focusing on wholesale pricing tiers, synthesis scalability, and procurement protocols for bulk buyers.
Wholesale Pricing Tiers vs Retail Gram Costs
Understanding the cost structure of CAS 179162-55-1 requires distinguishing between research-grade retail pricing and industrial bulk contracts. Retail suppliers often list small quantities, such as 25 grams, at premium rates to cover packaging and handling for laboratory use. However, commercial manufacturing requires kilogram to ton-scale quantities, where the bulk price per unit weight decreases significantly due to economies of scale in raw material sourcing and reaction optimization.
The molecular formula C21H21NO4 and molecular weight of 351.39 g/mol dictate specific stoichiometric requirements during synthesis. Efficient production minimizes waste and solvent usage, directly impacting the final cost. Below is a representative pricing structure based on volume commitments typically offered by top-tier manufacturers.
| Quantity Tier | Purity Specification | Estimated Lead Time | Commercial Application |
|---|---|---|---|
| 10g - 100g | >98% (HPLC) | 3-5 Days | Method Development / Lab Scale |
| 1kg - 10kg | >98.5% (HPLC) | 2-3 Weeks | Pilot Plant / Pre-clinical |
| 100kg - 1 Ton | >99.0% (HPLC) | 4-6 Weeks | Commercial Manufacturing |
| Custom Volume | GMP / USP / EP | Negotiated | Full Scale Production |
It is important to note that pricing is subject to fluctuations in raw material costs, particularly for the pentyloxyphenyl precursors and isoxazole formation reagents. Long-term contracts often lock in rates, protecting buyers from market volatility. When evaluating quotes, buyers should request detailed Certificates of Analysis (COA) to verify that impurities profiles match their specific process requirements.
Global Manufacturer Supply Chain Capabilities
The synthesis of this compound typically involves the condensation of hydroxylamine derivatives with appropriate ketones or aldehydes, followed by cyclization to form the isoxazole ring. Maintaining high yields during this synthesis route is essential for cost-effective production. Advanced manufacturers utilize continuous flow chemistry or optimized batch reactors to enhance safety and reproducibility.
As a global manufacturer, NINGBO INNO PHARMCHEM CO.,LTD. maintains robust logistics networks to ensure timely delivery regardless of destination. Our quality control laboratories employ high-performance liquid chromatography (HPLC) and nuclear magnetic resonance (NMR) to validate structural integrity. This compound serves as a key Micafungin intermediate, necessitating strict control over regioisomers and residual solvents.
For process chemists evaluating supply options, technical support is as valuable as the product itself. When sourcing high-purity Antifungal synthesis precursor, buyers should prioritize vendors who offer custom synthesis services to adjust purity profiles or particle size distributions. Our facility is equipped to handle custom modifications, ensuring the material integrates seamlessly into downstream reactions without requiring additional purification steps that could erode overall yield.
Supply chain resilience also involves regulatory compliance. Documentation such as DMF (Drug Master File) support, REACH compliance, and safety data sheets (SDS) are standard requirements for international shipment. Ensuring that the manufacturing process adheres to environmental and safety standards mitigates risk for the downstream pharmaceutical producer.
Requesting Volume Quotes and Lead Times
Procuring 4-[5-(4-Pentyloxyphenyl)isoxazol-3-yl]benzoic acid for commercial use requires a formal request for quotation (RFQ) that specifies technical and logistical needs. Buyers should provide detailed specifications regarding acceptable impurity limits, packaging preferences (e.g., double-lined cardboard drums or HDPE containers), and destination ports. This information allows the manufacturer to calculate accurate freight costs and production schedules.
Lead times vary based on current inventory levels and the complexity of the required quality testing. For standard industrial purity grades, stock may be available for immediate shipment. However, customized batches requiring specific chromatographic profiles may require additional production time. It is advisable to initiate contact with potential suppliers at least 30 days prior to the required delivery date to accommodate synthesis and quality assurance protocols.
Effective communication during the quoting phase ensures alignment on technical expectations. Discussing the intended application helps the supplier recommend the most cost-effective grade. Whether the material is intended for early-stage research or full-scale commercial production, transparency regarding volume forecasts enables the manufacturer to reserve capacity and raw materials, preventing supply disruptions.
In conclusion, securing a reliable supply of CAS 179162-55-1 is a strategic decision impacting the broader production of antifungal therapeutics. By partnering with an experienced provider like NINGBO INNO PHARMCHEM CO.,LTD., organizations can ensure access to high-quality intermediates, competitive pricing, and the technical support necessary for successful pharmaceutical development.