1-Bromononafluorobutane CAS 375-48-4 | Bulk Supply & COA
COA Parameters and Analytical Metrics for 1-Bromononafluorobutane (CAS 375-48-4)
NINGBO INNO PHARMCHEM CO.,LTD. delivers 1-Bromononafluorobutane (CAS 375-48-4) as a critical fluorinated building block for advanced material science and pharmaceutical intermediates. Our production adheres to strict analytical protocols, ensuring consistency for every batch. As a reliable global manufacturer, we provide comprehensive documentation to support your R&D and procurement workflows. Analytical metrics extend beyond simple assay values; our QC laboratory evaluates trace halogenated impurities that may arise from incomplete fluorination or side reactions. These impurities, even at ppm levels, can alter reaction kinetics in subsequent coupling steps. The batch-specific COA provides a full chromatogram overlay to verify impurity profiles against reference standards.
For precise specifications, please refer to the batch-specific COA. The following table outlines standard physical and chemical metrics verified during our manufacturing process:
| Parameter | Specification | Test Method |
|---|---|---|
| Appearance | Clear liquid | Visual Inspection |
| Boiling Point | 43-44°C | Distillation |
| Density | 1.904 g/mL | Densitometer |
| Purity (GC) | Please refer to the batch-specific COA | Gas Chromatography |
| Moisture Content | Please refer to the batch-specific COA | Karl Fischer Titration |
Field Engineering Note: During summer loading operations, the vapor pressure of 1-Bromononafluorobutane increases significantly due to its low boiling point. We strongly recommend utilizing vented IBCs or pressure-relief mechanisms to prevent liner deformation. Standard non-vented containers are prone to bulging under thermal stress, which can compromise seal integrity during transit. Our technical team can provide vapor pressure curves to assist in the design of storage and transfer systems.
Purity Grade Classifications: 97% Technical vs. 99%+ Reagent and Electronic Grades
We supply nonafluorobutyl bromide in multiple grades to match specific application requirements. The 97% technical grade is optimized for bulk organic synthesis intermediate applications where cost-efficiency is paramount. This grade serves as a seamless drop-in replacement for competitor codes such as PC5309 or TBr-4, maintaining identical reactivity profiles while offering superior supply chain reliability. When substituting competitor products, procurement managers often overlook the impact of trace acid impurities on catalyst longevity. Our 97% technical grade is processed to minimize perfluorinated acid residues, ensuring that your palladium or nickel catalysts maintain activity over multiple cycles. This reduces total cost of ownership by extending catalyst life, a critical factor in high-volume manufacturing.
For sensitive applications requiring higher assay levels, we offer 99%+ reagent grades. These batches undergo additional distillation steps to minimize trace impurities that could interfere with palladium-catalyzed cross-coupling reactions. Selecting the appropriate grade ensures optimal yield without over-specifying purity for robust synthesis route protocols. Our engineering team can assist in grade selection based on your downstream reaction sensitivity and yield targets.
Bulk Packaging Specifications: UN-Rated Drums, Liner Compatibility, and Fill Volumes
Packaging configurations are designed to ensure physical integrity and safe handling. Standard options include UN-rated 210L steel drums with HDPE liners and 1000L IBCs. Liner materials are selected for chemical resistance to halogenated hydrocarbons. Liner compatibility is critical for halogenated solvents. We utilize high-density polyethylene (HDPE) liners that resist permeation and chemical attack. Polypropylene liners may exhibit stress cracking under prolonged exposure to brominated fluorocarbons. Our packaging engineering team validates liner integrity through accelerated aging tests to ensure zero leakage during extended storage periods. Fill volumes are calculated to accommodate thermal expansion, preventing over-pressurization during temperature fluctuations.
For inquiries regarding bulk price structures and customized packaging requirements, our sales team provides transparent quotes based on volume and destination. All shipments comply with standard transport regulations for hazardous liquids. We do not provide environmental certifications or REACH registration claims; our focus remains on physical packaging integrity and reliable logistics execution.
Physical Property Thresholds: Boiling Point, Density, and Vapor Pressure Tolerances
The physical properties of perfluorobutyl bromide dictate handling procedures and equipment selection. The boiling point range of 43-44°C requires closed-loop transfer systems to minimize vapor loss and operator exposure. Density is measured at 1.904 g/mL, which is significantly higher than water and most organic solvents. This density differential impacts phase separation behavior in multi-component mixtures. Storage vessels must be rated for positive pressure due to vapor pressure characteristics at ambient temperatures. Venting systems must include vapor recovery or scrubbing capabilities to meet workplace safety standards.
Operational Insight: Due to the high density of 1.904, any aqueous contamination introduced during transfer will settle rapidly at the bottom of the vessel. Operators must purge bottom-drain valves before sampling to avoid skewed moisture readings. Failure to do so can result in false-high Karl Fischer results, leading to unnecessary batch rejection. This behavior is consistent across all grades and must be accounted for in automated sampling protocols.
Quality Control Protocols: GC Assay, Karl Fischer Moisture, and Heavy Metal Limits
Quality assurance is integral to our operations. Each batch undergoes GC assay for purity determination, Karl Fischer titration for moisture content, and heavy metal screening. These protocols ensure the product meets the requirements for industrial purity standards. Detailed results are provided in the COA accompanying each shipment. Our QC laboratory utilizes calibrated instrumentation and validated methods to ensure data accuracy. Heavy metal limits are strictly controlled to prevent catalyst poisoning in downstream applications. We maintain a comprehensive quality management system to ensure traceability and consistency across all production runs.
Frequently Asked Questions
What is the minimum order quantity (MOQ) for 1-Bromononafluorobutane?
MOQ varies by grade and packaging type. Please contact our sales team for current availability and minimum thresholds.
Can you provide samples for evaluation?
Yes, samples are available for technical evaluation. Contact us to arrange sample shipment and documentation.
What is the HS code for customs declaration?
The HS code for 1-Bromononafluorobutane is 2903793090.
Do you offer drop-in replacements for specific competitor codes?
Yes, our 97% grade is a direct replacement for codes like PC5309 and TBr-4, offering identical technical parameters with enhanced supply reliability.
How is the product packaged for international shipping?
We use UN-rated 210L drums or 1000L IBCs with chemically resistant liners. Packaging is optimized for safe transport and thermal management.
Sourcing and Technical Support
NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing high-quality 1-Bromononafluorobutane with consistent technical support. Our engineering team is available to assist with integration into your synthesis processes and to address any technical queries. Explore our 1-Bromononafluorobutane fluorinated building block for detailed product information.
To request a batch-specific COA, SDS, or secure a bulk pricing quote, please contact our technical sales team.