Industrial Purity Specifications for N,N-Dimethyl-1-Dodecanamine (CAS 112-18-5)
- Technical Grade Assay: Target purity ≥98.0% via Gas Chromatography (GC) for optimal downstream quaternization.
- Physical Constants: Boiling point 265.2°C at 760 mmHg; Density 0.787 g/mL at 20°C ensures consistent reaction stoichiometry.
- Supply Chain Security: Bulk procurement available directly from NINGBO INNO PHARMCHEM CO.,LTD. with verified COA documentation.
In the realm of specialty surfactant synthesis and cationic intermediate production, the consistency of raw material specifications is paramount. N,N-Dimethyldodecylamine, commonly identified by CAS 112-18-5, serves as a critical precursor for manufacturing quaternary ammonium compounds, amine oxides, and betaine surfactants. For process chemists and procurement managers, understanding the nuanced differences between technical grade and refined purity levels is essential for maintaining high reaction yields and minimizing downstream purification costs.
This technical overview delineates the critical quality attributes, manufacturing parameters, and procurement standards required for industrial-scale operations involving this long-chain tertiary amine.
Key Physicochemical Properties and Identification
Accurate identification and handling of N-dodecyl-N,N-dimethylamine begin with a rigorous verification of its physical constants. Deviations in density or refractive index often indicate the presence of homologous impurities, such as tetradecyl or decyl derivatives, which can alter the hydrophile-lipophile balance (HLB) of the final surfactant product.
| Parameter | Specification / Value | Test Method |
|---|---|---|
| CAS Number | 112-18-5 | Registry |
| Molecular Formula | C14H31N | Calculated |
| Molecular Weight | 213.40 g/mol | MS |
| Assay (Purity) | ≥ 98.0% (Industrial Grade) | GC (Area %) |
| Boiling Point | 265.2 ± 3.0 °C at 760 mmHg | Distillation |
| Density | 0.787 g/mL at 20 °C | ASTM D4052 |
| Refractive Index | 1.4375 (n20/D) | ASTM D1218 |
| Water Content | ≤ 0.1% | Karl Fischer |
| Appearance | Colorless to Light Yellow Liquid | Visual / APHA |
Maintaining low water content is particularly critical when this amine is used in exothermic quaternization reactions with alkyl halides. Excess moisture can lead to hydrolysis side reactions, reducing the active matter content of the final quaternary ammonium salt.
Manufacturing Process and Synthesis Route
The commercial production of this tertiary amine typically involves the catalytic alkylation of dimethylamine with dodecyl alcohol or dodecyl chloride. The efficiency of the synthesis route directly impacts the impurity profile. High-quality industrial purity is achieved through fractional distillation under vacuum to separate the target C12 chain length from lighter (C10) and heavier (C14-C16) homologs.
Advanced manufacturing process controls focus on minimizing secondary amine formation and ensuring complete methylation. For buyers evaluating suppliers, it is crucial to request a detailed COA that specifies the percentage of secondary amines and residual solvents. Inconsistent batch quality can lead to variability in foam stability and biocidal efficacy in the final formulated products.
Interpreting COA Data for CAS 112-18-5
When reviewing Certificate of Analysis documents, procurement teams should look beyond the primary assay percentage. A comprehensive quality assessment includes:
- Gas Chromatography Profile: Ensure the main peak area corresponds to ≥98% and check for significant peaks near the retention time of the target compound.
- Color (APHA): Oxidation during storage can darken the liquid. A low APHA value indicates fresh production and proper nitrogen blanketing during storage.
- Amine Value: Titration data should align with the theoretical amine value of approximately 262 mg KOH/g.
Reliable data transparency is a hallmark of a trusted partner. When sourcing high-purity N,N-Dimethyl-1-dodecanamine, buyers should verify that the supplier provides batch-specific traceability and retains samples for dispute resolution.
Impact of Assay ≥98% on Downstream Synthesis
The purity of the starting amine dictates the quality of downstream derivatives. In the production of lauryl dimethyl amine oxide, impurities can lead to unreacted amines that affect the pH stability of personal care formulations. Similarly, in the synthesis of biocides, homologous impurities may alter the spectrum of antimicrobial activity.
Industrial users prioritizing yield optimization should specify a minimum assay of 98.0% by GC. This standard minimizes the need for post-reaction stripping or purification, thereby reducing energy consumption and overall production costs. Furthermore, consistent purity ensures reproducible viscosity and solubility characteristics in the final surfactant blends.
Bulk Procurement and Global Supply Standards
Securing a stable supply chain for fatty amines requires partnering with a global manufacturer capable of scaling production to meet fluctuating market demands. Pricing volatility in the chemical sector often correlates with raw fatty alcohol availability and energy costs. Therefore, establishing long-term contracts with verified producers is advisable to lock in favorable bulk price agreements.
NINGBO INNO PHARMCHEM CO.,LTD. stands as a premier facility equipped to handle large-volume orders with strict adherence to international quality management systems. Our infrastructure supports bulk shipment via ISO tanks or drummed packaging, ensuring product integrity during transit. By controlling the supply chain from synthesis to delivery, we mitigate the risks associated with third-party trading companies.
Safety, Storage, and Logistics
Proper handling is essential due to the corrosive and toxic nature of this compound. The material is classified under Hazard Class 8 (Corrosive) with UN number 2735. Storage conditions should maintain temperatures below 30°C in a well-ventilated area, away from strong oxidizing agents and acids. Containers must be kept tightly closed to prevent moisture absorption and oxidation.
For international trade, the Harmonized System (HS) Code 2921199090 is typically applied. Buyers should ensure all safety data sheets (SDS) are updated according to GHS standards, highlighting hazards such as skin corrosion (H314) and aquatic toxicity (H410).
Conclusion
Selecting the right grade of N,N-Dimethyldodecylamine is a strategic decision that impacts both the technical performance of surfactant formulations and the economic efficiency of the manufacturing process. By prioritizing verified purity specifications, robust COA documentation, and reliable supply partners, chemical manufacturers can ensure consistent product quality.
For technical inquiries regarding specification sheets or to discuss custom synthesis requirements, NINGBO INNO PHARMCHEM CO.,LTD. offers dedicated support from our process chemistry team. We are committed to delivering high-performance intermediates that meet the rigorous demands of the global surfactant and agrochemical industries.