In the dynamic realm of pharmaceutical synthesis, specialized chemical compounds serve as indispensable building blocks for advanced therapeutic agents. Among these, 1-Methyl-4-(4-piperidinyl)piperazine dihydrochloride, identified by its CAS number 1219979-73-3, stands out as a crucial pharmaceutical intermediate. This compound, typically presenting as a white crystalline powder, boasts a molecular formula of C10H23Cl2N3 and a molecular weight of 256.216. Its high purity, generally maintained at ≥98.0%, ensures its reliability and effectiveness in demanding synthetic processes. NINGBO INNO PHARMCHEM CO.,LTD. recognizes the pivotal role of such high-quality intermediates in the progress of modern medicine.

The distinct chemical structure of 1-Methyl-4-(4-piperidinyl)piperazine dihydrochloride, characterized by a piperazine core with appended piperidinyl and methyl groups, contributes to its stability and solubility, which are critical for its utility in various chemical reactions. Its white crystal powder form facilitates ease of handling and processing within industrial and laboratory environments. The precise molecular weight and consistent assay levels are rigorously controlled to meet the stringent quality standards required for pharmaceutical-grade materials. To preserve these essential characteristics, proper storage is paramount: the compound should be kept in a cool, well-ventilated place, away from direct heat and moisture, preventing any degradation and maintaining its intrinsic efficacy for future use.

The primary and most significant application of 1-Methyl-4-(4-piperidinyl)piperazine dihydrochloride is its integral role in the synthesis of Brigatinib. Brigatinib is a powerful tyrosine kinase inhibitor, a targeted therapy widely used in the treatment of non-small cell lung cancer (NSCLC), particularly in cases involving ALK (anaplastic lymphoma kinase) mutations. The intricate multi-step synthesis of such sophisticated drugs heavily relies on intermediates that provide the necessary foundational chemical framework. This compound serves as that vital scaffold, enabling the construction of the final active pharmaceutical ingredient (API). Its specificity and reactivity make it an ideal precursor for complex drug molecules designed to combat challenging diseases.

Beyond its direct link to Brigatinib, the versatility of the piperazine backbone within this compound hints at its potential utility in the development of other pharmaceutical agents. Piperazine derivatives are well-established in medicinal chemistry, appearing in drugs for a range of conditions, including neurological disorders, infectious diseases, and cardiovascular ailments. This broad potential underscores the importance of a consistent and high-quality supply. For commercial and industrial applications, 1-Methyl-4-(4-piperidinyl)piperazine dihydrochloride is typically offered in 25 kg drums, ensuring secure and efficient transport. However, NINGBO INNO PHARMCHEM CO.,LTD. also provides flexible packaging solutions tailored to meet diverse customer specifications, whether for large-scale production runs or smaller research batches.

The global pharmaceutical industry’s relentless pursuit of innovation and new therapies necessitates a robust and reliable supply chain for critical intermediates. The demand for high-purity compounds like 1-Methyl-4-(4-piperidinyl)piperazine dihydrochloride continues to grow, driven by ongoing research and increasing treatment needs. For pharmaceutical companies worldwide, identifying a dependable manufacturer and supplier is crucial. Factors such as consistent product quality, competitive price, and efficient delivery mechanisms are paramount when looking to buy or purchase such specialized chemicals. NINGBO INNO PHARMCHEM CO.,LTD. prides itself on its advanced manufacturing infrastructure and deep expertise in producing pharmaceutical-grade compounds, ensuring adherence to international quality standards and timely fulfillment of orders.

As a leading entity in the research, development, and production of fine chemicals and pharmaceutical intermediates, NINGBO INNO PHARMCHEM CO.,LTD. possesses extensive experience with compounds like 1-Methyl-4-(4-piperidinyl)piperazine dihydrochloride. Our capabilities span a wide range of organic synthesis, including the production of various bromides, boric acids, thiophenes, indoles, imidazoles, thiazoles, and other piperazine and pyrazine derivatives. We are equipped to handle manufacturing volumes from 100 kg to 100 metric tons annually, specializing in processes involving up to five synthetic steps. Our commitment to innovation is further demonstrated through our continuous flow process development and state-of-the-art equipment. We excel in complex reactions requiring high temperature, high pressure, nitration, oxidation, and continuous distillation, offering scalable and efficient solutions that support our clients' most ambitious projects. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supporting your ventures with top-tier products and unparalleled service.