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2,2'-Anhydro-5-methyluridine: A Vital Pharmaceutical Intermediate

2,2'-Anhydro-5-methyluridine (CAS: 22423-26-3) stands as a pivotal chemical compound in the realm of advanced pharmaceutical synthesis. Also recognized by its synonyms such as 2,2'-O-Anhydro-5-methyluridine, 2,2'-Anhydro-D-thymidine, and 2,2'-Cyclothymidine, this versatile nucleoside derivative is an indispensable building block for numerous complex organic molecules. Its unique structural features make it highly valuable in the development of cutting-edge medicinal compounds, particularly within the nucleoside analog family.


Delving into its chemical and physical characteristics, 2,2'-Anhydro-5-methyluridine possesses a molecular formula of C10H12N2O5 and a molecular weight of approximately 240.21300 g/mol. It typically appears as a white to off-white crystalline powder, indicative of its high purity and stable form. Key physical properties include a melting point ranging from 217.0 to 221.0 °C, a boiling point estimated at 452 °C, and a density of 1.88 g/cm³. Furthermore, it exhibits a flash point of 227.2 °C and an index of refraction of 1.772. These well-defined properties ensure consistent performance and reliability in various chemical processes.


Our commitment to quality ensures that 2,2'-Anhydro-5-methyluridine meets stringent specifications. Each batch undergoes rigorous analysis, with an assay (HPLC) typically yielding ≥98.0% purity. Additional quality control measures, such as loss on drying, are kept below 0.5%, affirming the exceptional quality and stability of the product. This high level of purity is paramount for its application in sensitive pharmaceutical processes, where impurities can compromise the efficacy and safety of the final drug product.


The primary application of 2,2'-Anhydro-5-methyluridine lies in its critical role as an intermediate of pharmaceuticals. It is particularly significant in the synthesis of nucleoside analogs, which are a class of compounds widely explored for their therapeutic potential. These analogs are vital components in the development of antiviral drugs, used to combat infections like HIV and hepatitis, and also play a crucial role in the creation of anticancer medications by interfering with DNA and RNA replication in rapidly dividing cells. Its precise chemical structure facilitates complex reactions, enabling the creation of novel drug candidates and contributing significantly to medical advancements.


For optimal preservation and longevity, 2,2'-Anhydro-5-methyluridine should be stored in a cool, well-ventilated, and dry place. Proper storage conditions are essential to maintain its integrity, chemical stability, and ensure maximum shelf life, safeguarding its quality for critical pharmaceutical applications. We recommend storing it in its original packaging, typically a 25 kg drum, or as per specific customer requirements to best suit individual needs.


As a leading manufacturer and supplier, we pride ourselves on providing high-quality 2,2'-Anhydro-5-methyluridine globally. We offer competitive price options for various order quantities, from laboratory-scale research to bulk industrial production. Our robust supply chain ensures efficient and reliable delivery, making the buy or purchase process seamless for our clients. Whether you require a small quantity for research and development or a large volume for commercial manufacturing, our dedicated team is ready to assist with your specific requirements, including custom packaging and comprehensive technical support. Partner with us for your 2,2'-Anhydro-5-methyluridine needs and experience unparalleled quality and service.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

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