2,3,5,6-Tetraaminopyridine Trihydrochloride, identified by CAS number 34981-10-7, stands as a highly significant chemical compound in various scientific and industrial domains. This heterocyclic compound features a pyridine ring adorned with four amine groups, further stabilized by three hydrochloride counterions. Its distinctive molecular structure, characterized by the molecular formula C5H12Cl3N5 and a molecular weight of 248.54 g/mol, confers upon it a unique set of chemical and biological properties, making it invaluable for advanced research and commercial applications.

The physical appearance of 2,3,5,6-Tetraaminopyridine Trihydrochloride is typically a brown solid. Ensuring its purity, often at 95% or higher, is crucial for its performance in sensitive applications. For optimal stability and prolonged shelf life, it is recommended to store this compound under an inert atmosphere at room temperature, protecting it from moisture and light. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing this compound with consistent quality and purity, adhering to stringent manufacturing standards.

The applications of 2,3,5,6-Tetraaminopyridine Trihydrochloride span a wide array of fields:

• In Chemistry: It serves as a fundamental building block in the sophisticated synthesis of complex organic molecules. Its amine groups readily participate in various reactions, including nucleophilic substitution, enabling the creation of novel compounds with tailored properties. This makes it an indispensable tool for synthetic chemists developing new chemical entities.


• In Biology and Medicinal Chemistry: The compound's unique structure allows it to function as a ligand in coordination chemistry, playing a role in the study of enzyme mechanisms. Research suggests its potential as a nitric oxide (NO) carrier, influencing vascular responses, which could lead to applications in cardiovascular therapies. Furthermore, some pyridine derivatives, including this compound, have shown promise in exhibiting antioxidant activity, contributing to the reduction of oxidative stress in biological systems. Its interactions with various biological targets, such as enzymes and receptors, are also under investigation for drug development purposes.


• In Industry: This compound is actively utilized in the production of a diverse range of industrial chemicals, including dyes and pigments. Its chemical reactivity makes it a valuable intermediate for creating colored compounds and other specialty chemicals.


• In Materials Science: 2,3,5,6-Tetraaminopyridine Trihydrochloride acts as a versatile ligand for the formation of coordination polymers, Metal-Organic Frameworks (MOFs), and Covalent Organic Frameworks (COFs). These advanced materials are gaining prominence for their applications in gas storage, catalysis, and separation technologies. It has also been explored in the synthesis of high-performance polymers like polybenzimidazoles (PBIs), enhancing their solubility and thermal stability for applications such as fuel cells.

The synthesis of 2,3,5,6-Tetraaminopyridine Trihydrochloride typically involves multi-step processes, often commencing with the nitration of pyridine derivatives, followed by reduction and amination steps. The final trihydrochloride salt is formed by treating the tetraamine with hydrochloric acid. Recent advancements also include one-pot synthesis methods that streamline the production, maintaining high yields and purity. In industrial settings, these processes are scaled up using large reactors and precise control of reaction conditions to ensure consistent quality and efficiency.

The compound's effectiveness as a polydentate ligand stems from its four amine groups, which enable stable chelation with various transition metals. This ability to form strong coordination bonds is central to its utility in catalysis and materials science. Compared to its free base form, the trihydrochloride salt offers enhanced stability and water solubility, making it more practical for various experimental and industrial applications, as it is less susceptible to hygroscopicity and oxidation.

As a professional manufacturer and supplier of high-quality chemical compounds, NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing researchers and industrial clients with reliable access to 2,3,5,6-Tetraaminopyridine Trihydrochloride. We understand the critical importance of purity and consistency in chemical synthesis and research. For those looking to buy or purchase this versatile chemical, we offer competitive price options directly from our facilities. Our dedication to excellence ensures that every batch meets rigorous quality standards, supporting innovation across chemistry, biology, and materials science. Connect with us to explore how NINGBO INNO PHARMCHEM CO.,LTD. can fulfill your specific requirements for 2,3,5,6-Tetraaminopyridine Trihydrochloride and other advanced chemical intermediates.