3,5-Dibromopyrazin-2-amine (CAS 24241-18-7) stands as a significant compound in the realm of advanced chemical synthesis and pharmaceutical development. Recognized by synonyms such as 3,5-Dibromo-2-pyrazinamine and 2-Amino-3,5-dibromo-1,4-diazine, this compound is highly valued for its unique chemical structure and reactivity, making it an indispensable building block in various intricate chemical processes.

Chemically, 3,5-Dibromopyrazin-2-amine presents as a white to light yellow crystalline powder. Its molecular formula is C4H3Br2N3, with a molecular weight of 252.89 g/mol. Key physical properties include a melting point ranging from 114 to 117 °C, a boiling point of approximately 294.6 °C at 760 mmHg, and a flash point of 131.9 °C. The compound exhibits a density of 2.287 g/cm3 and typically boasts a minimum purity of 97% or higher, ensuring its reliability for demanding applications. For optimal preservation, it is recommended to store 3,5-Dibromopyrazin-2-amine in a refrigerator within an inert atmosphere, keeping the container tightly closed when not in use to maintain its integrity.

The applications of 3,5-Dibromopyrazin-2-amine are extensive and varied, primarily serving as an essential intermediate in the synthesis of complex materials and pharmaceutical raw intermediates. It plays a pivotal role in the preparation of conjugated polymers, which are critical for advanced neurotoxin detection systems. Furthermore, this compound is a vital intermediate in the synthesis of rho kinase (ROCK) inhibitors, underscoring its importance in medical research and drug development, particularly in areas related to cardiovascular diseases and cancer.

Beyond these, 3,5-Dibromopyrazin-2-amine is instrumental in the synthesis of other valuable chemical entities. It can be utilized to produce 2-amino-5-bromopyrazin-3-thiol, 2-amino-3,5-bis(p-methoxyphenyl)-1,4-pyrazine, and 3,7-dihydroimidazo[1,2a]pyrazine-3-ones, showcasing its versatility. Its synthesis can be achieved efficiently through the bromination of 2-aminopyrazine using N-bromosuccinimide (NBS). Interestingly, it reacts with sodium dicyanocuprate to yield mono and dicyanation products, and has been reported in the formation of 2-aminothiazolopyrazines when reacted with isothiocyanates. Research has also indicated its ability to inhibit cyclic nucleotide phosphodiesterase (PDE) enzymes and demonstrate cytotoxic effects on cancer cells in vitro, highlighting its potential in therapeutic applications.

NINGBO INNO PHARMCHEM CO.,LTD. is a leading manufacturer and supplier of high-quality 3,5-Dibromopyrazin-2-amine. We adhere to stringent quality control standards to ensure the purity and effectiveness of our products for all industrial and research needs. When you are looking to buy or purchase this essential chemical, we offer competitive price options for various quantities, from small research batches to large-scale industrial supplies. Our commitment to excellence makes us a preferred choice for researchers and chemical companies worldwide. For detailed product specifications, safety data sheets, and to inquire about the current price, please contact NINGBO INNO PHARMCHEM CO.,LTD. We are dedicated to providing superior products and reliable service to facilitate your scientific and industrial endeavors.