2'-Deoxyadenosine-5'-monophosphate (dAMP), a crucial deoxyribonucleotide, stands as a fundamental building block of deoxyribonucleic acid (DNA), the very blueprint of life. This indispensable compound, also known by its synonyms such as 2'-Deoxyadenosine 5'-phosphate, plays a pivotal role in numerous biological processes, particularly in the intricate mechanisms of DNA synthesis and repair. Its significance extends beyond fundamental biology, finding extensive application as a vital intermediate in the pharmaceutical industry.

Identified by its Chemical Abstracts Service (CAS) number 653-63-4, dAMP possesses a precisely defined chemical structure, represented by the molecular formula C10H14N5O6P and a molecular weight of 331.22200. These specific molecular identifiers underscore its consistent and reliable nature in various scientific and industrial contexts. The compound presents as a white to pale yellow powder, a characteristic appearance that further aids in its identification and quality assessment. Its physical properties are equally well-defined, with a melting point recorded at 148ºC, a boiling point at 753.5ºC, a flash point at 409.5ºC, and a density of 2.17 g/cm³. It exhibits good solubility in aqueous solutions, making it versatile for various experimental setups and formulations.

The primary application of 2'-Deoxyadenosine-5'-monophosphate lies in its capacity as a pharmaceutical intermediate. It is an essential precursor in the synthesis of various pharmaceutical compounds, contributing to the development of new drugs and therapies. Beyond its role in drug manufacturing, dAMP is also extensively utilized in biochemical research. Scientists employ it to delve into complex adenosine-based cellular interactions, which are crucial for understanding cellular function and disease progression. For instance, it has been instrumental in the synthesis of novel photoaffinity labels, allowing for detailed investigation into how DNA interacts with other molecules and how DNA damage occurs and is subsequently repaired. Studies also explore its behavior in different conditions, observing its photosensitized degradation primarily under acidic environments, an important consideration for formulation stability.

The quality and purity of 2'-Deoxyadenosine-5'-monophosphate are paramount for its sensitive applications. Rigorous quality control measures ensure that the product consistently meets a high standard, typically demonstrating an assay purity of ≥98.0% as determined by High-Performance Liquid Chromatography (HPLC). This high level of purity guarantees reliable results in research and optimal performance in pharmaceutical synthesis. For optimal longevity and to maintain its integrity, dAMP should be stored in a cool, well-ventilated place, often recommended at -20°C for long-term preservation. It is available in convenient packaging options, such as 25 kg drums, with flexibility to accommodate diverse customer requirements for specific quantities.

For research institutions, pharmaceutical companies, and chemical enterprises seeking a dependable 2'-Deoxyadenosine-5'-monophosphate supplier, ensuring a consistent and high-quality source is vital. When considering where to buy this essential deoxyribonucleotide, prospective customers should look for a reputable manufacturer with a strong track record in producing high-purity biochemicals. Factors such as competitive price, reliable delivery, and comprehensive technical support are key considerations for any purchase. Investing in a quality product from a trusted source ensures the integrity of research findings and the efficacy of downstream pharmaceutical applications.