2-(Trifluoromethoxy)benzoic acid, identified by its Chemical Abstracts Service (CAS) number 1979-29-9, stands as a pivotal organic compound in advanced chemical synthesis. Known by various synonyms such as o-trifluoromethoxybenzoic acid, this compound's molecular formula is C8H5F3O3, with a molecular weight of 206.11900. It is recognized for its unique chemical structure, incorporating both a trifluoromethoxy group and a carboxylic acid functionality, which renders it highly valuable in diverse synthetic pathways.
This versatile chemical intermediate typically presents as a white to light yellow crystalline powder. Its physical and chemical characteristics are well-defined, ensuring its utility in precise applications. Key properties include a density of 1.206 g/cm³, a melting point ranging between 78ºC and 80ºC, a boiling point of approximately 190.7ºC, and a flash point of 70.3ºC. These specifications are crucial for handling, storage, and application, enabling chemists and researchers to work with confidence and precision.
Quality assurance is paramount for such specialized intermediates. High-grade 2-(Trifluoromethoxy)benzoic acid is supplied with an assay of ≥98.0%, guaranteeing its purity for demanding reactions. Moisture content is meticulously controlled, typically maintained at ≤0.2%, to preserve its stability and reactivity. This commitment to purity ensures optimal performance in complex synthetic processes, minimizing side reactions and maximizing yields.
The primary application of 2-(Trifluoromethoxy)benzoic acid lies in its role as an organic synthesis intermediate. Its unique trifluoromethoxy group is particularly significant in modern chemistry. The incorporation of fluorine atoms can dramatically alter the physicochemical properties of molecules, influencing factors such as lipophilicity, metabolic stability, and binding affinity in drug design. Consequently, this compound serves as a crucial building block in the development of sophisticated molecules across various industries.
In the pharmaceutical industry, 2-(Trifluoromethoxy)benzoic acid is highly sought after for synthesizing novel drug candidates. Its distinctive chemical features enable the creation of pharmacologically active compounds with improved efficacy and reduced side effects. Similarly, in the agrochemical sector, it contributes to the development of advanced pesticides, herbicides, and fungicides that are more effective and environmentally targeted. Beyond these, it finds use in the production of specialty chemicals, including dyes and performance materials, where precise structural modifications are required.
For researchers and manufacturers worldwide, reliable sourcing of high-quality chemical intermediates like 2-(Trifluoromethoxy)benzoic acid is essential. It is typically packaged in 25 kg drums, though custom packaging options are often available to meet specific customer requirements. Proper storage in a cool, ventilated place is recommended to maintain product integrity and extend shelf life.
As a critical component in R&D and industrial production, the demand for 2-(Trifluoromethoxy)benzoic acid remains consistent. Leading suppliers are dedicated to providing consistent quality and availability. For those looking to source this valuable chemical, understanding the product specifications and engaging with reputable manufacturer and supplier networks is key to a seamless purchase. Inquiries regarding price and bulk buy options are readily addressed by expert sales teams, ensuring that researchers and industrial clients can procure this essential intermediate efficiently for their innovative projects.
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