4-Bromo-2-nitrobenzoic acid, identified by its CAS number 99277-71-1, stands as a pivotal chemical compound widely utilized across various sectors of the chemical industry. This organic synthesis intermediate plays a crucial role in the creation of complex molecules, making it indispensable for researchers and manufacturers alike. With its distinct molecular structure, it offers a versatile building block for advanced chemical reactions.

Known by several synonyms including Benzoic acid, 4-bromo-2-nitro- and 2-nitro-4-bromobenzoic acid, this compound possesses the molecular formula C7H4BrNO4 and a molecular weight of 246.01500. Its physical characteristics include an appearance ranging from off-white to pale yellow powder, or even white to gray to brown powder or crystal. Key physical properties underscore its stability and utility: a melting point typically between 165-169ºC, a boiling point of approximately 368.6ºC, and a flash point of 176.7ºC. The compound exhibits a density of 1.892 g/cm3 and is soluble in methanol, facilitating its use in various solvent-based processes.

The applications of 4-Bromo-2-nitrobenzoic acid are remarkably diverse. Primarily, it serves as a critical intermediate in organic synthesis. Its bromine and nitro groups provide reactive sites, allowing it to participate in a wide array of chemical transformations. Notably, it undergoes Negishi-type coupling reactions in the presence of palladium-phosphine catalysis, demonstrating its utility in forming carbon-carbon bonds, a cornerstone of modern organic chemistry. Beyond general synthesis, 4-Bromo-2-nitrobenzoic acid is particularly significant as an intermediate in the synthesis of Lonafarnib, a compound with potential anticancer properties. This specific application highlights its importance in pharmaceutical research and development, contributing to the advancement of new therapeutic agents.

At NINGBO INNO PHARMCHEM CO.,LTD., we ensure the highest quality of 4-Bromo-2-nitrobenzoic acid. Our product adheres to stringent specifications, typically boasting an assay of ≥98.0% and a moisture content of ≤0.2%. This commitment to purity guarantees optimal performance in sensitive applications. For safe handling and storage, it is recommended to keep the product in a cool, well-ventilated, and dry place, sealed at room temperature, protecting it from light and moisture. While generally stable, appropriate precautions should be taken given its classification as an irritant. Safety data sheets provide detailed information on handling, storage, and emergency procedures, ensuring responsible use.

Packaging for 4-Bromo-2-nitrobenzoic acid is typically available in 25 kg drums, with options for customized packaging to meet specific customer requirements. As a reliable manufacturer and supplier, NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing high-quality chemical intermediates to the global market. For those looking to buy or purchase this essential compound, we offer competitive price options and dependable delivery. Our expertise in chemical manufacturing positions us as a preferred partner for your sourcing needs, ensuring a consistent supply of premium 4-Bromo-2-nitrobenzoic acid for your research, development, and industrial applications.