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4-Fluoroindoline (CAS 552866-98-5): Key Intermediate for Advanced Synthesis

4-Fluoroindoline (CAS 552866-98-5) stands as a crucial chemical compound, widely recognized for its pivotal role as an intermediate in various organic synthesis processes. With its chemical name being 4-Fluoroindoline and CAS Number 552866-98-5, this compound is also known by its synonym, 4-fluoro-2,3-dihydro-1H-indole. While occasionally referenced with a "hydrochloride" suffix in some contexts, the fundamental properties and applications tied to CAS 552866-98-5 primarily relate to the base 4-Fluoroindoline molecule (C8H8FN), making it a versatile building block for chemists globally.


NINGBO INNO PHARMCHEM CO.,LTD. proudly presents 4-Fluoroindoline with stringent quality control, ensuring an assay of ≥97.0% purity. This high level of purity is essential for its application in sensitive chemical reactions where contaminant-free materials are paramount. Its physical appearance is typically a white to off-white solid, indicating its stable crystalline form under standard conditions.


Delving into its physical and chemical characteristics, 4-Fluoroindoline exhibits a molecular formula of C8H8FN and a molecular weight of approximately 137.154 g/mol. It possesses a density of 1.2±0.1 g/cm³, highlighting its compact molecular structure. The boiling point is recorded at 215.7±29.0 °C at 760 mmHg, suggesting its thermal stability, while its flash point of 84.2±24.3 °C is crucial for safe handling and storage considerations. Furthermore, with a low vapor pressure of 0.1±0.4 mmHg at 25°C and an index of refraction of 1.538, these parameters collectively define its unique chemical profile, allowing for precise control in synthetic pathways.


The primary application of 4-Fluoroindoline is as an intermediate in organic synthesis. Its indoline core, combined with a fluorine substituent, renders it highly valuable in the creation of more complex molecules. In the realm of pharmaceutical research and development, such fluoro-substituted heterocyclic compounds are particularly sought after. They serve as essential building blocks for synthesizing active pharmaceutical ingredients (APIs) and other bioactive compounds, contributing significantly to drug discovery efforts. Beyond pharmaceuticals, its utility extends to material science and other areas requiring specialized chemical structures, making it an indispensable component in advanced chemical manufacturing.


For optimal preservation of its quality and purity, 4-Fluoroindoline should be stored in a cool, ventilated place, ideally sealed and away from moisture. NINGBO INNO PHARMCHEM CO.,LTD. ensures reliable packaging, typically in 25 kg drums, with flexibility to accommodate specific customer requirements, emphasizing safe and secure delivery of this valuable compound.


As a dedicated 4-Fluoroindoline manufacturer and supplier, NINGBO INNO PHARMCHEM CO.,LTD. is committed to upholding the highest standards of product quality and customer service. We understand the critical importance of reliable chemical supply chains for research and industrial applications. Our focus is on providing 4-Fluoroindoline that consistently meets the rigorous demands of modern organic synthesis. For those interested to buy 4-Fluoroindoline, we offer competitive price structures and ensure efficient logistics. We are a trusted partner for anyone looking to purchase 4-Fluoroindoline in various quantities, backed by our expertise and commitment to excellence in chemical production.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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