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2-Bromo-5-formylthiazole: A Vital Intermediate for Chemical Synthesis

NINGBO INNO PHARMCHEM CO.,LTD. is proud to present 2-Bromo-5-formylthiazole, a high-quality organic intermediate critical for a diverse range of chemical applications. With its unique chemical structure, characterized by the presence of both a bromine atom and a formyl group on the thiazole ring, this compound (CAS No. 464192-28-7) stands as a foundational building block for complex molecules.


Product Specifications:
Chemical Name: 2-Bromo-5-formylthiazole
CAS No.: 464192-28-7
Molecular Formula: C4H2BrNOS
Molecular Weight: 192.03 g/mol
Appearance: Typically observed as a white to yellow crystalline powder
Assay: ≥98.0%


Versatile Applications in Organic Synthesis:
2-Bromo-5-formylthiazole is indispensable in the field of organic synthesis. Its reactivity makes it a key starting material for numerous chemical transformations. The bromine atom at position 2 is highly reactive, enabling a variety of cross-coupling reactions, such as Suzuki-Miyaura coupling, Heck coupling, and Buchwald-Hartwig amination. These reactions allow for the efficient formation of carbon-carbon and carbon-heteroatom bonds, leading to the construction of diverse and complex heterocyclic systems. The formyl group at position 5 also provides a versatile handle for further derivatization, including reduction to alcohols, oxidation to carboxylic acids, or formation of imines and oximes.


Beyond its role in forming new bonds, 2-Bromo-5-formylthiazole is extensively utilized in the preparation of a wide array of other organic compounds. These include pharmaceutical intermediates, agrochemicals, and specialty chemicals. The thiazole scaffold itself is a privileged structure in medicinal chemistry, often found in compounds exhibiting significant biological activities such as anti-inflammatory, antitumoral, antifungal, and antiviral properties. Thus, this intermediate is crucial for researchers and manufacturers aiming to synthesize novel drug candidates or bioactive molecules.


Scientific Research and Laboratory Use:
In scientific research and laboratory settings, 2-Bromo-5-formylthiazole serves as a valuable tool for exploring new reaction pathways and synthesizing custom organic molecules. Its predictable reactivity profile allows chemists to design intricate synthetic routes, pushing the boundaries of chemical innovation. Whether for fundamental studies in heterocyclic chemistry or for the development of advanced materials, this compound provides a reliable and high-purity reagent.


Quality Assurance and Storage:
At NINGBO INNO PHARMCHEM CO.,LTD., we are committed to providing products of the highest quality. Each batch of 2-Bromo-5-formylthiazole undergoes rigorous quality control checks to ensure it meets our strict assay specifications and purity standards. For optimal preservation of its integrity and reactivity, 2-Bromo-5-formylthiazole should be stored in a clean, dry, and cool place, protected from direct sunlight and rain. Proper storage ensures its stability for extended periods, making it a dependable chemical for your projects.


Sourcing and Partnership:
As a reliable manufacturer and supplier, NINGBO INNO PHARMCHEM CO.,LTD. ensures consistent availability and competitive price for 2-Bromo-5-formylthiazole. We offer flexible packaging options customized to customer needs, whether for small-scale laboratory experiments or larger industrial production. To buy or purchase this essential organic intermediate, or to inquire about bulk orders, please reach out to our sales team. We are dedicated to supporting your chemical synthesis endeavors with high-quality products and efficient service.

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