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4-(Trifluoromethoxy)phenyl Chlorothioformate: A Key Organic Synthesis Intermediate

4-(trifluoromethoxy)phenyl chlorothioformate, identified by its CAS number 2251-66-3, stands as a critical chemical compound in the realm of organic synthesis. This versatile intermediate plays a pivotal role in the creation of various complex organic molecules, making it indispensable for research and industrial applications across the globe. Its unique molecular structure, characterized by the trifluoromethoxy group and the chlorothioformate moiety, imparts specific reactivity, enabling its use in diverse synthetic pathways.


The chemical formula for 4-(trifluoromethoxy)phenyl chlorothioformate is C8H4ClF3O2S, with a molecular weight of 256.63. While some physical properties are yet to be fully characterized, available data indicates a boiling point of 96 °C at 11 Torr and a predicted density of 1.507±0.06 g/cm3. These properties are crucial for handling, storage, and application in various chemical processes, ensuring its suitability for precise reactions.


Quality is paramount when dealing with chemical intermediates, and 4-(trifluoromethoxy)phenyl chlorothioformate is no exception. Our stringent quality control measures ensure that the product supplied meets the highest industry standards. Key specifications include an assay of ≥98.0% purity and a maximum water content of ≤0.50%. This high level of purity guarantees optimal performance in sensitive organic synthesis reactions, minimizing impurities and maximizing reaction yield and selectivity.


The primary application of 4-(trifluoromethoxy)phenyl chlorothioformate lies in its function as an organic synthesis intermediate. It serves as a building block for synthesizing a wide range of pharmaceuticals, agrochemicals, and other specialty chemicals. Its reactivity allows for the introduction of the trifluoromethoxy-phenylthioformate group into target molecules, which can be crucial for enhancing desired properties or enabling further transformations. This makes it a valuable asset for chemists developing novel compounds and improving existing synthetic routes.


To maintain the integrity and quality of 4-(trifluoromethoxy)phenyl chlorothioformate, it is typically supplied in 25kg drums. Custom packaging solutions can also be designed to meet specific customer requirements, ensuring safe and efficient transport and handling. Proper storage is essential: the compound should be stored in a cool place, with the container tightly closed in a dry and well-ventilated area. Adhering to these storage guidelines helps preserve its chemical stability and reactivity over time.


As a dedicated chemical manufacturer and supplier, NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing high-quality 4-(trifluoromethoxy)phenyl chlorothioformate to global markets. Our extensive experience in chemical production, coupled with robust quality assurance systems, ensures that every batch meets rigorous standards. We understand the critical nature of reliable supply chains for our clients' production needs. For those looking to buy or purchase 4-(trifluoromethoxy)phenyl chlorothioformate, NINGBO INNO PHARMCHEM CO.,LTD. offers competitive price options without compromising on product quality or service. We invite potential partners and clients to inquire about our offerings and discuss how we can meet their specific requirements. Our commitment to excellence makes us a preferred choice for sourcing essential chemical intermediates.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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