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5-Bromo-2-fluorobenzonitrile (CAS 179897-89-3) stands as a highly significant organic chemical intermediate, playing a pivotal role in the synthesis of various pharmaceutical active ingredients and advanced materials. This fluorinated benzonitrile derivative is recognized for its unique chemical structure, which grants it versatile reactivity and makes it an indispensable building block in complex chemical syntheses. As a leading manufacturer and supplier of specialty chemicals, NINGBO INNO PHARMCHEM CO.,LTD. proudly offers high-purity 5-Bromo-2-fluorobenzonitrile, ensuring exceptional quality for diverse industrial and research applications.
Possessing a molecular formula of C7H3BrFN and a molecular weight of 200.01 g/mol, 5-Bromo-2-fluorobenzonitrile typically appears as a white powder. Its physical and chemical properties include a density of approximately 1.7±0.1 g/cm3, a boiling point around 220.4±20.0 °C at 760 mmHg, and a melting point ranging from 76 to 81 °C. The compound also exhibits a flash point of 87.1±21.8 °C, a vapor pressure of 0.1±0.4 mmHg at 25°C, and an index of refraction of 1.578. These precise specifications underscore its consistent quality and suitability for demanding chemical processes.
One of the primary applications of 5-Bromo-2-fluorobenzonitrile is its crucial role as an intermediate in the synthesis of Febuxostat (CAS 144060-53-7). Febuxostat is a widely prescribed medication used for the long-term management of hyperuricemia in patients with gout, by reducing uric acid levels in the blood. The purity and reliability of 5-Bromo-2-fluorobenzonitrile are paramount in ensuring the efficacy and safety of the final pharmaceutical product.
Beyond its use in Febuxostat production, 5-Bromo-2-fluorobenzonitrile is valued as a versatile building block in a broader spectrum of chemical syntheses. Its dual halogen substituents, bromine and fluorine, offer differing reactivities, enabling selective substitution reactions vital for creating complex molecular structures. This makes it an attractive precursor for the development of new pharmaceutical APIs, including compounds with potential antitumour and anti-inflammatory properties, essential for modern drug discovery efforts. Furthermore, as a fluorinated benzonitrile building block, it contributes to research in advanced materials, such as those used in organic light-emitting diodes (OLEDs), where precisely engineered molecular structures are critical for performance.
NINGBO INNO PHARMCHEM CO.,LTD. adheres to rigorous quality control standards, ensuring that our 5-Bromo-2-fluorobenzonitrile meets an assay specification of ≥98.0%. We offer flexible packaging options, typically in 25 kg drums, and can accommodate specific customer requirements. For optimal preservation of its properties and purity, the product should be stored in a cool, ventilated place, protected from light and moisture.
As a dedicated manufacturer and supplier, NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing high-quality chemical intermediates to the global market. We invite prospective clients to inquire about the price and availability of 5-Bromo-2-fluorobenzonitrile. To buy or purchase this essential chemical, please reach out to our sales team. Partner with us for your chemical sourcing needs and experience the reliability and quality that define NINGBO INNO PHARMCHEM CO.,LTD.
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