In the dynamic landscape of pharmaceutical development, the availability of high-quality intermediates is paramount for the efficient and successful synthesis of active pharmaceutical ingredients (APIs). NINGBO INNO PHARMCHEM CO.,LTD. is proud to present a crucial compound in this field: Acalabrutinib Intermediate, with CAS No. 1420478-88-1. This advanced intermediate is indispensable for the production of Acalabrutinib, a next-generation Bruton's Tyrosine Kinase (BTK) inhibitor that has revolutionized the treatment of certain hematological malignancies.

Acalabrutinib, known commercially as Calquence, represents a significant leap forward in targeted cancer therapy. It functions by selectively inhibiting BTK, a protein crucial for the survival and proliferation of B-cells, making it highly effective against B-cell cancers. Approved by the Food and Drug Administration (FDA) for conditions such as chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), and mantle cell lymphoma (MCL), Acalabrutinib offers long-term survival benefits and an improved safety profile compared to some traditional treatments. Its targeted mechanism of action minimizes damage to healthy cells, leading to better patient outcomes and reduced side effects.

The intermediate we provide, chemically known as (2S)-2-(8-Amino-1-Bromoimidazo[1,5-a]Pyrazin-3-yl)-1-Pyrrolidinecarboxylic Acid Phenylmethyl Ester, is a complex yet vital molecule in the synthesis pathway of Acalabrutinib. With a molecular formula of C18H18BrN5O2 and a molecular weight of 416.27, this compound is manufactured with stringent quality control measures to ensure exceptional purity, typically exceeding 98%. Its consistent quality is critical, as any deviation can significantly impact the efficacy and safety of the final API.

At NINGBO INNO PHARMCHEM CO.,LTD., we understand the demanding requirements of the pharmaceutical industry. Our commitment to excellence is reflected in our advanced manufacturing processes and rigorous quality assurance protocols. We ensure that every batch of Acalabrutinib Intermediate (CAS 1420478-88-1) meets the highest international standards, making it suitable for both advanced research applications and large-scale pharmaceutical production. This intermediate is ideal for scientific research, laboratory reagents, and analytical purposes, where precise and reliable chemical components are essential.

As a dedicated manufacturer and reliable supplier of pharmaceutical intermediates, NINGBO INNO PHARMCHEM CO.,LTD. is poised to support your research and production needs. We pride ourselves on offering competitive prices without compromising on quality. For those looking to buy or purchase high-purity Acalabrutinib Intermediate, our team is ready to assist with detailed product specifications, comprehensive documentation, and efficient logistics. We are committed to fostering long-term partnerships by providing unparalleled service and a consistent supply of this critical pharmaceutical building block.