In the expansive realm of pharmaceutical chemistry, certain compounds stand out for their pivotal roles in the development of advanced medical diagnostics. One such critical substance is 5-(Acetamido)-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide, identified by its unique CAS number, 31127-80-7. This high-purity chemical intermediate is indispensable for various high-value synthetic processes, particularly within the medical imaging sector.

The chemical identity of this compound is well-defined. Its molecular formula is C16H20I3N3O7, and it possesses a molecular weight of 747.06 g/mol. Known by several synonyms in the industry, including Iohexol Intermediate, Iohexol Related Compound A, Iodixanol Impurity B, and 5-Acetylamino-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide, its nomenclature reflects its structural characteristics and its close relationship to widely used diagnostic agents. These alternative names are often encountered in research and development, underscoring its broad recognition and utility.

From a physical and chemical perspective, 5-(Acetamido)-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide typically presents as a white to off-white solid or powder. It exhibits a melting point in the range of 274-276°C, indicating its thermal stability. While its boiling point is predicted to be around 746.1±60.0 °C, and its density at 2.289±0.06 g/cm3, these properties underscore its robust chemical structure. In terms of solubility, it is sparingly soluble when heated in DMSO and slightly soluble when heated in Methanol. More effectively, it demonstrates solubility in a 1:1 mixture of Methanol and Water, facilitating its use in various reactions. Optimal storage conditions recommend keeping it at 2-8°C, in a cool, dry place, and ideally under an inert atmosphere, given its hygroscopic nature, to maintain its integrity and extend its shelf life.

The primary application of 5-(Acetamido)-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide is its crucial role as an intermediate in the synthesis of cutting-edge imaging agents. Specifically, it is a vital precursor in the production of Iohexol, a non-ionic, low-osmolar contrast medium extensively used in diagnostic medical imaging, including computed tomography (CT) scans, angiography, and urography. The synthesis of such sophisticated agents demands intermediates of the highest purity and consistency to ensure the safety and efficacy of the final pharmaceutical product. Its involvement in creating these diagnostic tools highlights its profound impact on modern healthcare, enabling clearer and more precise medical diagnoses.

At NINGBO INNO PHARMCHEM CO.,LTD., we specialize in the meticulous production and supply of high-quality chemical compounds like 5-(Acetamido)-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide (CAS 31127-80-7). Our commitment to excellence ensures that every batch meets stringent purity standards, typically above 97%, guaranteeing reliability for sensitive pharmaceutical applications. We leverage advanced manufacturing processes and rigorous quality control measures to deliver products that consistently exceed industry expectations, supporting the critical needs of our clients in the pharmaceutical and research sectors.

For research institutions and pharmaceutical companies seeking a dependable manufacturer and supplier of 5-(Acetamido)-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide, NINGBO INNO PHARMCHEM CO.,LTD. stands as a trusted partner. We offer competitive price options for both small-scale research quantities and bulk orders. To buy or purchase this essential Iohexol intermediate, or to inquire about our product specifications and current availability, please reach out to our dedicated sales team. We are committed to providing exceptional service and tailored solutions to meet your specific chemical sourcing requirements.