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Cancer, a disease characterized by uncontrolled cell growth and proliferation, presents one of the most formidable challenges in modern medicine. A fundamental aspect of cancer therapy is the induction of programmed cell death, or apoptosis, in malignant cells. This carefully orchestrated cellular self-destruction process is a natural mechanism to eliminate damaged or unwanted cells, and its dysregulation is a hallmark of cancer. Harnessing and enhancing apoptosis in cancer cells is therefore a primary goal for oncologists and researchers alike.
Understanding the intricate molecular pathways that trigger and execute apoptosis is critical for developing effective anti-cancer strategies. While various pathways exist, the intrinsic mitochondrial pathway plays a pivotal role. This pathway is heavily influenced by the state of mitochondrial function, particularly the delicate balance of energy production and the integrity of the mitochondrial membrane. Research chemicals that can specifically manipulate these mitochondrial processes are invaluable for dissecting these complex mechanisms.
Atractyloside Sodium Salt (CAS 100938-11-2) emerges as a significant tool in this pursuit. As a potent inhibitor of the mitochondrial adenine nucleotide translocase (ANT), it directly impacts the cell's energy production machinery. By blocking the essential exchange of ADP and ATP across the mitochondrial inner membrane, Atractyloside Sodium Salt disrupts cellular respiration. This disruption can lead to mitochondrial dysfunction, increased production of reactive oxygen species, and the release of pro-apoptotic factors from the mitochondria, ultimately driving the cell towards self-destruction. This makes it a prime candidate for studying the mechanisms of apoptosis induction.
For researchers focusing on oncology, leveraging compounds like Atractyloside Sodium Salt allows for precise experimental control. It provides a means to directly probe the involvement of ANT and mitochondrial integrity in cancer cell death. By observing the effects of this inhibitor, scientists can gain deeper insights into:
As a chemical manufacturer and supplier, we recognize the critical need for high-quality research compounds. We offer Atractyloside Sodium Salt, manufactured to exacting standards, ensuring purity and consistency for your experiments. If you are looking to buy this essential compound for your cancer research or other related studies, we provide a reliable supply chain and competitive pricing. Partner with us to procure the tools you need to advance your understanding of apoptosis and develop next-generation cancer therapies. Contact us today to get a quote for your research needs.
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to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
