The intricate world of cellular energy production hinges on a delicate balance of molecular exchanges within the mitochondria. At the heart of this process lies the Mitochondrial Adenine Nucleotide Translocase (ANT), a crucial transporter responsible for shuttling ADP into the mitochondrial matrix and ATP out. Disruptions to this vital exchange can have profound implications for cellular health, playing a significant role in various physiological and pathological conditions, including neurodegenerative diseases, cardiovascular disorders, and cancer.

Understanding the ANT's function and how its activity can be modulated is paramount for advancing our knowledge in these fields. This is where specific molecular tools, such as inhibitors, become indispensable. Among the most well-characterized inhibitors of ANT is Atractyloside Sodium Salt, a naturally derived compound that has become a cornerstone in research labs worldwide. As a leading manufacturer and supplier of high-quality chemicals, we are committed to providing researchers with reliable access to compounds like Atractyloside Sodium Salt (CAS 100938-11-2) to facilitate their groundbreaking work.

Atractyloside Sodium Salt is known for its potent and specific inhibition of ANT. By binding to the transporter, it effectively blocks the movement of ADP and ATP across the inner mitochondrial membrane. This blockade disrupts oxidative phosphorylation, the primary mechanism by which cells generate energy in the form of ATP. The consequence is a cascade of cellular events, including a significant reduction in ATP synthesis and a potential increase in mitochondrial membrane permeability, which can trigger programmed cell death, or apoptosis.

The utility of Atractyloside Sodium Salt extends across numerous research applications. Scientists employ it to:

• Investigate cellular bioenergetics: By inhibiting ANT, researchers can quantify the dependence of cellular processes on mitochondrial ATP production.
• Study apoptosis pathways: The compound's ability to induce mitochondrial dysfunction and trigger apoptosis makes it a valuable tool for dissecting the complex mechanisms of programmed cell death. This is particularly relevant in cancer research, where inducing apoptosis in tumor cells is a key therapeutic strategy.
• Develop and validate drug targets: As ANT plays a role in various diseases, Atractyloside Sodium Salt serves as a reference compound in the development of novel therapeutics aimed at modulating mitochondrial function. If you are looking to buy research chemicals for drug discovery, consider our offerings.
• Explore toxicological mechanisms: Understanding how interference with energy metabolism leads to cellular damage is crucial in toxicology. This chemical provides a controlled way to induce such damage for study.

For researchers and pharmaceutical companies seeking a reliable source for this critical research chemical, purchasing from a reputable manufacturer is essential. We are a dedicated supplier of Atractyloside Sodium Salt, offering competitive prices and ensuring consistent purity and quality. Our commitment to serving the scientific community means you can confidently buy from us, knowing you are receiving a product that meets stringent standards. We invite you to inquire about our supply capabilities and experience the advantage of sourcing directly from a trusted chemical manufacturer in China.