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Understanding the chemical properties of Trimethylsilylacetylene (CAS 1066-54-2) is paramount for its effective utilization in synthesis. At NINGBO INNO PHARMCHEM CO.,LTD., we provide this versatile compound, also known as Ethynyltrimethylsilane, to facilitate a wide range of chemical transformations. This guide aims to illuminate its key characteristics and how they benefit various applications.
Trimethylsilylacetylene is characterized by its colorless liquid appearance and a high assay of ≥98.0%, ensuring purity and reliability for critical reactions. Its molecular formula, C5H10Si, and molecular weight of 98.22, point to its role as a compact yet functional building block. The presence of the trimethylsilyl group offers a protective element to the ethynyl functionality, allowing for selective reactions and controlled deprotection when needed. This makes it an excellent example of a silane protected acetylene.
Key physical properties include a boiling point of 53 °C, a density of 0.695 g/mL at 25 °C, and a refractive index of n20/D 1.388. These properties contribute to its ease of handling as a liquid reagent. Chemically, it participates in a variety of reactions, including palladium-catalyzed ethynylation, nucleophilic additions, and cycloadditions. Its ability to act as a substrate in nickel-catalyzed cross-coupling reactions further broadens its synthetic scope.
The trimethylsilylacetylene chemical properties make it a preferred choice for organic synthesis building blocks. Researchers often leverage its reactivity in creating complex molecular architectures, including in the synthesis of pharmaceuticals and advanced materials. The compound is also integral to processes like chemical vapor deposition for polycarbosilane films, a testament to its versatility in material science.
When planning your next synthesis, consider the robust chemical profile of Trimethylsilylacetylene. NINGBO INNO PHARMCHEM CO.,LTD. is your reliable source for this essential reagent, supporting your endeavors in chemical research and production with high-quality products and technical understanding.
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