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The Advantages of Trimethylsilylacetylene: A Safer Alternative for Ethynylation

At NINGBO INNO PHARMCHEM CO.,LTD., we understand the challenges chemists face in handling reactive reagents. Trimethylsilylacetylene (CAS 1066-54-2), also known as Ethynyltrimethylsilane, offers a significant advantage over its gaseous counterpart, acetylene, particularly in terms of safety and ease of use. This makes it a preferred choice for a wide array of ethynylation and other synthetic applications.

Acetylene, while a fundamental building block, is a highly flammable gas that requires specialized equipment and stringent safety protocols for handling. In contrast, Trimethylsilylacetylene is a stable, colorless liquid. This physical property dramatically simplifies storage, transportation, and manipulation in the laboratory and industrial environments. The ability to reliably purchase Trimethylsilylacetylene in liquid form streamlines synthetic workflows and reduces operational risks.

The reactivity of Trimethylsilylacetylene is finely tuned, allowing it to participate effectively in key transformations like palladium-catalyzed cross-coupling reactions and nucleophilic attacks. As a silane protected acetylene, it offers controlled release of the ethynyl group, preventing uncontrolled reactions that can occur with free acetylene. This controlled reactivity is a critical aspect of its utility as an organic synthesis building block.

Furthermore, the trimethylsilylacetylene synthesis is well-established, ensuring consistent quality and availability. This reliability is crucial for researchers and manufacturers who depend on a steady supply of high-purity reagents for their processes. The compound's versatility extends to material science, where it's used in applications like chemical vapor deposition, further underscoring its broad applicability.

Choosing Trimethylsilylacetylene from NINGBO INNO PHARMCHEM CO.,LTD. means opting for a safer, more manageable, and equally effective solution for introducing ethynyl groups. Embrace the convenience and enhanced safety that this remarkable compound offers your chemical processes.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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WHY CHOSE US?

1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

FAQ

  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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Address: No.163 Ruiqing Rd.,Ningbo 315000 China
Phone: 86-574-87319282
Fax: 86-574-27912196
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