Custom Manufacturing, Project Outsourcing, your Trusted Partner from China
NINGBO INNO PHARMCHEM CO.,LTD. is deeply involved in the progression of pharmaceutical compounds that promise to alleviate significant patient suffering. Difelikefalin is one such compound, marking a new chapter in the management of chronic itch conditions.
The development of Difelikefalin showcases the power of targeted drug design. As a peripherally restricted drug, it targets kappa opioid receptors (KORs) specifically on nerve endings and immune cells, thereby avoiding the adverse central nervous system effects often associated with opioid medications. This precise targeting is what sets it apart and makes it particularly suitable for long-term treatment.
The primary clinical application where Difelikefalin has shown remarkable success is in treating pruritus in patients undergoing hemodialysis, a condition often referred to as CKD-aP. The intense itching experienced by these patients can severely impair their quality of life. NINGBO INNO PHARMCHEM CO.,LTD. is proud to contribute to therapies that provide such profound relief. The rigorous process of difelikefalin clinical trials has validated its efficacy and safety. These trials have consistently demonstrated that Difelikefalin effectively reduces the burden of itch, leading to significant improvements in patients' well-being.
Understanding the broader implications of Difelikefalin is crucial. While its primary use is for CKD-aP, the underlying mechanism as a difelikefalin kappa opioid receptor agonist suggests potential applications in other itch and pain management scenarios. Research continues to explore its full therapeutic spectrum, building on the strong foundation established by its success in treating chronic itch.
NINGBO INNO PHARMCHEM CO.,LTD. is committed to supporting the pharmaceutical industry with high-quality ingredients. Our role involves facilitating the journey of compounds like Difelikefalin from laboratory development to patient benefit. For researchers and developers, understanding the nuances of difelikefalin pruritus management and its overall impact on patient health is key to unlocking the full potential of this innovative peptide.
Manufacturing Facilities
Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
