Custom Manufacturing, Project Outsourcing, your Trusted Partner from China
At NINGBO INNO PHARMCHEM CO.,LTD., we are dedicated to advancing pharmaceutical solutions for complex health challenges. Difelikefalin, a sophisticated peptide, represents a significant breakthrough in managing conditions like uremic pruritus.
Difelikefalin operates as a peripherally restricted kappa opioid receptor (KOR) agonist. This means its action is localized to the peripheral nervous system, avoiding the central nervous system (CNS) side effects often associated with traditional opioids. This peripheral selectivity is a game-changer, allowing for effective relief from intense itching without causing sedation or cognitive impairment. For patients with chronic kidney disease, who often suffer from severe and persistent itching, this targeted approach offers substantial relief and improved quality of life.
The effectiveness of Difelikefalin in treating uremic pruritus, a common and distressing symptom in patients undergoing hemodialysis, has been well-documented in clinical studies. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing the high-quality pharmaceutical ingredients necessary for such advanced therapies. The precise difelikefalin pruritus management capabilities are attributed to its ability to modulate itch signals at their source, offering a direct and effective solution. This addresses a significant unmet medical need within the patient population.
The development of Difelikefalin highlights the growing importance of peptide therapeutics in modern medicine. As a difelikefalin kappa opioid receptor agonist, it exemplifies how targeted molecular design can lead to improved patient outcomes. The ongoing exploration of difelikefalin uses in various pruritic conditions further underscores its versatility and potential impact across a broader range of dermatological and systemic itch disorders.
Understanding the difelikefalin mechanism of action is key to appreciating its therapeutic advantage. By selectively activating peripheral KORs, it offers a safer and more effective alternative to treatments that may carry higher risks of systemic side effects. NINGBO INNO PHARMCHEM CO.,LTD. is proud to be a part of this therapeutic advancement, supporting research and development in innovative peptide-based medicines.
Manufacturing Facilities
Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
