O-Phthalaldehyde, identified by its CAS Registry Number 643-79-8, is a significant organic compound with the molecular formula Cu2088Hu2086Ou2082 and a molecular weight of 134.13. Also known by its synonyms like Opa or Benzene-1,2-dicarboxaldehyde, this chemical exists as a solid, typically in powder form at room temperature. Its physical properties include a melting point ranging from 54 to 57 u00baC and a flash point at 132 u00baC, with a density of approximately 1.13 g/cmu00b3. These fundamental characteristics make O-Phthalaldehyde a stable and manageable substance for various industrial processes.

The primary utility of O-Phthalaldehyde lies in its versatility as a chemical intermediate and a fine chemical. Its unique structure, featuring two aldehyde groups positioned adjacent to each other on a benzene ring, grants it high reactivity, particularly with amines. This reactivity is the basis for many of its key applications across diverse sectors.

One of the most well-known applications of O-Phthalaldehyde is in analytical chemistry. It is widely used as a derivatization reagent for the fluorescence detection of primary amines, amino acids, and proteins. In analytical techniques like High-Performance Liquid Chromatography (HPLC), O-Phthalaldehyde reacts rapidly with primary amines in the presence of a thiol (such as 2-mercaptoethanol) to form highly fluorescent isoindole derivatives. This derivatization step significantly enhances the sensitivity of detection, making it invaluable for analyzing complex biological samples, food products, and environmental samples where low concentrations of amino compounds need to be quantified accurately.

Beyond analytical applications, O-Phthalaldehyde serves as a crucial intermediate in the pharmaceutical industry. While not typically a final drug product itself, it is a building block for synthesizing various pharmacologically active compounds. Its reactive aldehyde groups can participate in condensation, addition, and cyclization reactions, leading to the formation of complex heterocyclic structures common in many drug molecules. Researchers and chemists utilize O-Phthalaldehyde in the synthesis pathways of specific APIs (Active Pharmaceutical Ingredients), contributing to the development and production of new medications.

Another significant application area is disinfection and sterilization. O-Phthalaldehyde solutions, commonly formulated as a 0.55% aqueous solution, are effective high-level disinfectants. They are particularly valued in healthcare settings for disinfecting heat-sensitive medical devices, such as endoscopes, which cannot withstand heat sterilization. The disinfectant action of O-Phthalaldehyde is attributed to its ability to react with proteins and other essential cellular components of microorganisms, including bacteria, viruses, fungi, and mycobacteria. Its efficacy, combined with relatively short contact times and a low odor compared to glutaraldehyde, makes it a preferred choice in many medical facilities.

Furthermore, O-Phthalaldehyde finds uses in the synthesis of specialty chemicals and materials. Its structure allows for unique polymerization reactions and the creation of polymers with specific properties. It can also be employed in synthesizing pigments, dyes, and other fine chemicals where its reactivity and structural features are advantageous.

The quality and purity of O-Phthalaldehyde are paramount, especially for sensitive applications like pharmaceutical synthesis and analytical chemistry. Manufacturers must adhere to strict quality control standards to ensure the product meets the required specifications, including purity levels, melting point, and the absence of impurities that could interfere with downstream processes or analyses.

The demand for high-quality O-Phthalaldehyde is driven by the growth in the healthcare sector, increasing use of advanced analytical techniques, and ongoing research in chemical synthesis. Reliable sourcing is essential for companies depending on this intermediate. NINGBO INNO PHARMCHEM CO.,LTD. is a prominent supplier of O-Phthalaldehyde (CAS 643-79-8), offering this product to meet the needs of pharmaceutical, chemical, and analytical industries worldwide. As a dedicated manufacturer and supplier of chemical raw materials, NINGBO INNO PHARMCHEM CO.,LTD. focuses on providing compounds like O-Phthalaldehyde with consistent quality and reliability. Businesses looking to buy or purchase O-Phthalaldehyde can obtain competitive price information and discuss bulk requirements, such as the typical MOQ of 130 kg, directly from the supplier. Sourcing directly from a reputable manufacturer and supplier like NINGBO INNO PHARMCHEM CO.,LTD. ensures access to product expertise and efficient supply chain management.