Di-Tert-Butyl Dicarbonate, commonly known as Boc Anhydride, with the CAS number 24424-99-5, stands as a pivotal chemical reagent in the realm of organic synthesis. This compound is primarily utilized for the introduction of the tert-butyloxycarbonyl (Boc) group, serving as a highly effective protecting group for amines. Its application spans across various sectors, playing an indispensable role in the creation of complex molecules.

The fundamental function of Boc Anhydride is to protect primary and secondary amines by converting them into their corresponding Boc-amides or carbamates. This protection is crucial in multi-step synthesis where the amine functionality needs to be temporarily masked to prevent unwanted reactions while transformations are carried out on other parts of the molecule. The Boc group is particularly favored due to its ease of introduction under mild conditions and its facile removal via acidic hydrolysis, typically using trifluoroacetic acid or hydrochloric acid, without affecting most other functional groups. This selective protection-deprotection strategy is a cornerstone of modern organic chemistry.

The versatility of Boc Anhydride makes it invaluable in several key industries. In the pharmaceutical sector, it is a fundamental building block and intermediate for the synthesis of numerous active pharmaceutical ingredients (APIs). The precise control over amine reactivity afforded by Boc protection is essential for constructing complex drug molecules efficiently and with high purity. It is also extensively used in peptide synthesis, where the stepwise coupling of amino acids requires the temporary protection of the amine group of the incoming amino acid residue. Beyond pharmaceuticals, Boc Anhydride finds applications in the synthesis of fine chemicals, agrochemicals, and even in the development of specialized polymers and materials. Its role as a raw material for various chemical processes highlights its broad utility.

Characteristically, Di-Tert-Butyl Dicarbonate is typically presented as a low melting crystalline solid or sometimes a liquid, with a melting point around 23 °C. This means it can exist in either solid or liquid form depending on ambient temperature. Its boiling point is noted around 56-57 °C at 0.5 mmHg, and it has a density of approximately 0.95 g/mL at 25 °C. The refractive index is around 1.409. It is sensitive to moisture and heat, necessitating storage at controlled temperatures, typically between 2-8°C, to maintain its stability and purity. High purity, often specified as over 99%, is critical for its efficacy in sensitive synthetic reactions. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing Boc Anhydride that meets stringent purity standards.

The manufacturing process for high-quality Boc Anhydride adheres to strict quality control measures. Suppliers often operate under quality management systems such as ISO 9001, ensuring consistency and reliability. For pharmaceutical applications, production may also follow principles aligning with GMP (Good Manufacturing Practice) standards to guarantee the suitability of the material for downstream processing into drug substances. Rigorous testing, including checks for purity, moisture content, and physical properties, is performed before the product is released. NINGBO INNO PHARMCHEM CO.,LTD. prioritizes quality assurance throughout its production and supply chain.

When considering the logistics, Di-Tert-Butyl Dicarbonate is available in various packaging sizes to suit different needs, ranging from smaller quantities like 1kg in aluminum foil bags to larger drums of 25kg. Shipping methods are typically determined by the order size and urgency, with options including express delivery for small samples or urgent orders, air shipping for moderate quantities (e.g., up to 500kg), and sea shipping for bulk orders exceeding 500kg. Sample availability is often provided to allow customers to verify quality before committing to a larger purchase. The minimum order quantity (MOQ) is typically around 1kg, although smaller sample sizes may be accommodated under specific terms.

If you are looking to secure a reliable supply of high-purity Di-Tert-Butyl Dicarbonate CAS 24424-99-5, NINGBO INNO PHARMCHEM CO.,LTD. stands as a dedicated manufacturer and supplier. We understand the critical importance of this reagent in your synthetic processes. For inquiries regarding the price of Boc Anhydride, details on how to buy or purchase specific quantities, or to request technical specifications and sample information, our team is ready to assist. We aim to facilitate a smooth and efficient transaction, ensuring you receive the quality product you require for your applications. Our commitment extends to providing clear product analysis reports before shipping, offering transparency and confidence in every batch.

Finding the right supplier for essential chemical raw materials like Boc Anhydride is crucial for the success and efficiency of your operations. NINGBO INNO PHARMCHEM CO.,LTD. is positioned to meet your demands with consistent quality and dependable service. Whether you are a research institution requiring laboratory quantities or a manufacturing facility needing bulk supply, we invite you to connect with us. Let us be your trusted partner for high-quality Di-Tert-Butyl Dicarbonate.