NINGBO INNO PHARMCHEM CO.,LTD. is pleased to present high-purity Nitazoxanide powder, identified by its Chemical Abstracts Service (CAS) number 55981-09-4. This active pharmaceutical ingredient (API) is renowned for its broad-spectrum efficacy, primarily recognized as a potent anthelmintic agent used to treat various parasitic infections. Its availability as a fine white crystalline powder makes it suitable for a wide range of pharmaceutical formulations, serving global health needs in combating parasitic diseases.

Nitazoxanide's chemical structure, defined by the molecular formula C12H9N3O5S and a molecular weight of 307.28, contributes to its unique pharmacological profile. Supplied as a solid powder, ensuring specified purity levels, such as 98% or higher, is paramount for its intended therapeutic applications. The physical characteristics, including its appearance as a white crystalline powder and a density around 1.29, are important parameters for quality control and formulation development by pharmaceutical manufacturers.

Beyond its well-established use against helminths and protozoa, Nitazoxanide demonstrates activity against certain anaerobic and micro-aerobic bacteria. Notably, studies have indicated its effectiveness against *Helicobacter pylori*, a common bacterium implicated in gastric ulcers and other digestive issues. This broad antibacterial action expands its potential therapeutic utility beyond traditional antiparasitic treatments, offering a multifaceted approach to managing various microbial and parasitic challenges.

Furthermore, Nitazoxanide has shown promise in treating viral infections, particularly in pediatric populations. It has been reported to have a beneficial effect on diarrhea caused by rotavirus, a leading cause of severe diarrheal illness in infants and young children worldwide. This antiviral property highlights the compound's remarkable versatility and its significance in addressing a range of infectious diseases affecting different age groups.

While the precise mechanism of action for all its activities is still under investigation, it is understood to interfere with critical energy metabolism pathways in susceptible organisms. In anaerobes, it is thought to inhibit enzyme-dependent electron transfer reactions involving pyruvate ferredoxin oxidoreductase (PFOR) enzymes, which are essential for their survival. This disruption of fundamental metabolic processes leads to the inhibition of growth and death of the pathogens.

For pharmaceutical companies formulating finished drug products, the quality and purity of the API are non-negotiable. High purity Nitazoxanide powder must meet stringent quality standards, often adhering to pharmacopoeial monographs such as those outlined in the United States Pharmacopeia (USP) or the British Pharmacopoeia (BP). Compliance with Good Manufacturing Practices (GMP) and quality management systems like ISO 9001 are also crucial indicators of a reliable API supply. NINGBO INNO PHARMCHEM CO.,LTD. is committed to supplying Nitazoxanide powder that meets these rigorous international quality standards, ensuring consistency and reliability for our customers.

The manufacturing process for high-purity Nitazoxanide requires precise chemical synthesis and stringent purification steps. Careful control of raw material inputs, reaction conditions, and crystallization processes is essential to achieve the desired polymorphic form, particle size distribution, and chemical purity required for downstream processing into tablets, suspensions, or other dosage forms. Consistency in these physical and chemical attributes is vital for batch-to-batch uniformity and predictable performance in pharmaceutical formulations.

Proper handling and storage are also critical for maintaining the quality of Nitazoxanide API powder. It is typically recommended to store the material sealed in a cool, dry place to protect it from moisture and degradation. For transportation, appropriate packaging such as aluminum foil bags within cartons is used to ensure the integrity and stability of the product during transit, safeguarding its quality from the point of manufacture to the customer's facility.

The versatility and broad spectrum of activity of Nitazoxanide make it a valuable compound in the pharmaceutical armamentarium against various infectious agents. Its effectiveness against parasites, bacteria like *H. pylori*, and viruses such as rotavirus underscores its importance in global health. The demand for high-quality Nitazoxanide API powder continues as healthcare providers rely on this compound for treating a range of conditions.

As a dedicated manufacturer and experienced supplier of pharmaceutical raw materials, NINGBO INNO PHARMCHEM CO.,LTD. is a reliable source for high-purity Nitazoxanide CAS 55981-09-4 powder. We understand the critical requirements of the pharmaceutical industry for quality, consistency, and timely delivery. For pharmaceutical companies and formulators looking to buy or purchase this essential API, obtaining accurate price information and understanding the supply chain logistics are key steps. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing comprehensive support to facilitate your procurement process, ensuring you receive a product that meets the highest standards required for manufacturing safe and effective medicines.