Lamivudine Powder, identified by its CAS number 134678-17-4, stands as a cornerstone active pharmaceutical ingredient (API) in the global fight against major viral diseases, specifically Human Immunodeficiency Virus (HIV) and chronic Hepatitis B virus (HBV) infections. As a high-quality, pharmaceutical-grade raw material, Lamivudine Powder is essential for manufacturers producing vital antiviral medications.

This versatile API is a synthetic nucleoside analogue. Its mechanism of action is well-established: it acts as a potent inhibitor of viral reverse transcriptase in HIV and viral DNA polymerase in HBV. By competing with natural deoxycytidine triphosphate, Lamivudine triphosphate (the intracellularly phosphorylated form of Lamivudine) gets incorporated into nascent viral DNA chains, causing premature chain termination and thus inhibiting viral replication. This targeted action makes it highly effective in reducing viral load in infected individuals.

High purity is paramount for Lamivudine Powder used in pharmaceutical applications. Typically required at a minimum purity of 99%, stringent quality control measures, including testing by High-Performance Liquid Chromatography (HPLC), ensure that the product meets the rigorous standards set by international pharmacopeias such as USP and BP. The physical form is a white powder, indicating its refined state suitable for further processing into various dosage forms like tablets or oral solutions.

The primary therapeutic applications of Lamivudine are the treatment of HIV infection, usually as part of highly active antiretroviral therapy (HAART) in combination with other antiviral agents, and the treatment of chronic Hepatitis B. While used at different dosages for these conditions (higher for HIV, lower for HBV), its role in both is to suppress viral activity, helping to manage the disease, improve patient outcomes, and reduce the risk of progression to more severe conditions like cirrhosis or liver cancer (in HBV) or AIDS (in HIV).

For chronic Hepatitis B, Lamivudine has demonstrated efficacy in achieving seroconversion of the e-antigen and improving liver histology. However, it is known that long-term use in HBV patients can lead to the development of resistance mutations, particularly the YMDD mutation in the HBV polymerase. Despite this, it remains a valuable treatment option, especially in resource-limited settings or as part of initial therapy, often followed by or used in combination with other anti-HBV agents.

Reliable sourcing of pharmaceutical raw materials like Lamivudine Powder is critical for ensuring the consistent production of life-saving medicines. Manufacturers require a partner who understands the complexities of API production, quality assurance, regulatory compliance (such as GMP standards), and supply chain management. A reputable manufacturer adheres to strict production protocols to deliver a product that is not only pure and potent but also consistent batch-to-batch.

The chemical identifiers, including the molecular formula C8H11N3O3S and molecular weight 229.26, along with the EINECS number 603-844-3, are crucial for documentation and quality verification throughout the supply chain. Proper packaging and storage are also vital; keeping Lamivudine Powder in a cool, dry place ensures its stability and maintains its 2-year shelf life, protecting its integrity from manufacturing to formulation.

Packaging options typically include standard sizes like 1kg foil bags, 10 bags per carton, or 25kg drums, catering to various production scales from pilot batches to large-scale commercial manufacturing. The transport method, whether by air, sea, express, or special shipping line, is selected to ensure safe and timely delivery while maintaining product quality.

Choosing the right supplier of Lamivudine Powder is as important as the product quality itself. A good supplier provides comprehensive technical documentation, including Certificates of Analysis (COA) and Material Safety Data Sheets (MSDS), and offers support for regulatory submissions. They should also be able to provide samples for evaluation and testing before a large-scale purchase.

For pharmaceutical companies, researchers, and distributors seeking a trustworthy manufacturer and supplier of high-quality Lamivudine Powder (CAS 134678-17-4), NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing materials that meet the highest industry standards. We offer competitive price options for various quantities, supporting your production needs from small batches to bulk orders. To inquire about the current Lamivudine price, request a sample, or discuss your specific procurement requirements, please contact us. We are ready to facilitate your purchase and provide the necessary information and support to ensure a smooth and efficient transaction.