Custom Manufacturing, Project Outsourcing, your Trusted Partner from China
Preclinical drug development is a critical phase where understanding a drug candidate's behavior within biological systems is paramount. Efflux transporters, such as P-glycoprotein (P-gp) and Breast Cancer Resistance Protein (BCRP), are major determinants of drug pharmacokinetics and can significantly impact a drug's efficacy and safety profile. Elacridar hydrochloride, a potent inhibitor of these transporters, has become an indispensable tool for preclinical studies aimed at optimizing drug candidates.
Elacridar hydrochloride, known by its CAS number 143851-98-3 (or related CAS 143664-11-3 for the base form), is a third-generation modulator of ABCB1 (P-gp) and ABCG2 (BCRP). Its primary role in preclinical development is to mitigate the effects of these efflux pumps. By inhibiting P-gp and BCRP, Elacridar can enhance the absorption, distribution, and target site accumulation of various drugs, including chemotherapeutics and CNS-active agents. This leads to improved therapeutic outcomes and can help overcome mechanisms of drug resistance.
For pharmaceutical companies and contract research organizations (CROs), ensuring a reliable supply of high-purity Elacridar hydrochloride is essential for their preclinical pipelines. We are a leading manufacturer and supplier in China, offering Elacridar hydrochloride that meets rigorous quality specifications. Our commitment to purity and consistent quality allows researchers to confidently buy Elacridar hydrochloride for in vitro assays, animal studies, and pharmacokinetic profiling. Obtaining this compound from a trusted source streamlines the procurement process and supports efficient project timelines.
The strategic use of Elacridar hydrochloride in preclinical research involves understanding its impact on the bioavailability and efficacy of drug candidates. For instance, in oncology, it helps restore sensitivity to multidrug-resistant cancer cells. In neuroscience, it aids in assessing the potential for drugs to cross the blood-brain barrier. As a supplier, we provide competitive pricing and flexible ordering options, including bulk purchases, to meet the diverse needs of preclinical development. We invite you to contact us for a quote to explore how our high-quality Elacridar hydrochloride can advance your research and drug development efforts.
Manufacturing Facilities
Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
