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Essential Peramivir Intermediate: (1S,4R)-Methyl 4-aminocyclopent-2-enecarboxylate Tartrate

The compound (2R,3R)-2,3-dihydroxybutanedioic acid, methyl (1S,4R)-4-aminocyclopent-2-ene-1-carboxylate, identified by CAS number 419563-22-7, stands as a pivotal pharmaceutical intermediate. Also known by synonyms such as (1S,4R)-Methyl 4-aminocyclopent-2-enecarboxylate L-tartrate salt and (1S,4R)-Methyl 4-aminocyclopent-2-enecarboxylate (2R,3R)-2,3-dihydroxysuccinate, this high-purity compound is typically found as an off-white to light beige solid. Its critical role lies in the synthesis of Peramivir, a powerful antiviral agent against influenza.


With a molecular formula of C11H17NO8 and a molecular weight of 291.26, this compound exhibits a precise chemical architecture. It possesses a high boiling point of 499.3 degrees Celsius at 760 mmHg and a flash point of 255.8 degrees Celsius, indicating its thermal stability. Quality assurance is paramount, with typical specifications showing a purity of greater than or equal to 98% and a maximum moisture content of 0.5%. These robust physical and chemical properties ensure its reliability in demanding pharmaceutical processes, underscoring its value in complex synthetic pathways.


The primary application of this compound is its indispensable function as an intermediate for Peramivir (CAS: 229614-55-5). Peramivir is a critical neuraminidase inhibitor, playing a vital role in curbing the spread of influenza viruses within the human body. The precise stereochemistry of the intermediate, particularly its (1S,4R) and (2R,3R) configurations, is absolutely essential for the chiral synthesis of Peramivir. This specificity ensures that the final drug product possesses the required biological activity and efficacy, making the intermediate a cornerstone in antiviral drug development and production.


Maintaining the integrity of this specialized chemical requires meticulous storage and handling protocols. It is strongly recommended to store the compound in a -20 degrees Celsius freezer within a cool, dry, and well-closed container. Protection from moisture, strong light, and excessive heat is crucial to prevent degradation and maintain its specified purity and efficacy. The product is commonly packaged in 25kg cardboard drums, though packaging can be tailored to meet specific customer requirements. Adherence to these guidelines is vital for preserving the compound's quality throughout its shelf life, whether for research or industrial scale operations.


At NINGBO INNO PHARMCHEM CO.,LTD., we are a distinguished manufacturer and supplier dedicated to the research, development, and production of high-quality pharmaceutical intermediates, including this essential compound. Our commitment to excellence is reflected in our advanced capabilities, which encompass continuous flow process development, state-of-the-art equipment manufacturing, and the operation of pilot-scale workshops, supported by collaborations with large-scale production platforms. We specialize in a diverse range of reaction types, ensuring the production of intermediates with exceptional purity and consistency. The growing global demand for effective antiviral therapies, particularly for influenza, highlights the increasing need for reliable sources of key intermediates. Our expertise positions us uniquely to meet these demands, offering scalable solutions from kilograms to hundreds of tons annually.


For pharmaceutical companies and research institutions seeking a trusted source for (2R,3R)-2,3-dihydroxybutanedioic acid, methyl (1S,4R)-4-aminocyclopent-2-ene-1-carboxylate, NINGBO INNO PHARMCHEM CO.,LTD. offers competitive advantages. Our robust quality control systems ensure every batch meets stringent industry standards. Clients interested to buy or purchase this vital intermediate can easily inquire about its price and availability. We pride ourselves on transparent communication and efficient logistics, ensuring a seamless procurement process. Whether you require small quantities for research or bulk supplies for commercial production, our dedicated team is ready to provide tailored solutions and detailed product information. Partner with NINGBO INNO PHARMCHEM CO.,LTD. for your high-purity pharmaceutical intermediate needs.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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WHY CHOSE US?

1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

FAQ

  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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NINGBO INNO PHARMCHEM CO.,LTD.
Address: No.163 Ruiqing Rd.,Ningbo 315000 China
Phone: 86-574-87319282
Fax: 86-574-27912196
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