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The Farnesoid X Receptor (FXR) is a critical nuclear receptor that plays a pivotal role in regulating bile acid, lipid, and glucose metabolism, as well as inflammation and fibrosis. Obeticholic Acid (CAS 459789-99-2), a semi-synthetic bile acid derivative, has emerged as a potent and selective FXR agonist, offering significant promise in the treatment of various liver diseases. For researchers investigating these complex pathways, understanding the properties and applications of Obeticholic Acid is key.
Obeticholic Acid's primary mechanism of action involves activating FXR. This activation leads to a cascade of downstream effects, including the suppression of hepatic bile acid synthesis and the promotion of bile acid excretion. This regulatory function is particularly important in conditions characterized by cholestasis, such as primary biliary cholangitis (PBC), where bile acid accumulation can lead to liver damage. As a leading Obeticholic Acid manufacturer, we provide researchers with a high-quality compound to explore these therapeutic mechanisms.
Beyond its anticholeretic effects, Obeticholic Acid has also demonstrated anti-inflammatory and antifibrotic properties, making it a compound of great interest for non-alcoholic steatohepatitis (NASH). Studies have shown its ability to improve liver histology in preclinical models by reducing inflammation and fibrosis. When you buy Obeticholic Acid, you are acquiring a crucial research tool to investigate these multifaceted therapeutic benefits. Our company ensures that the Obeticholic Acid we supply meets stringent purity standards, critical for reproducible research results.
For those in the pharmaceutical industry looking to source Obeticholic Acid, choosing a reliable supplier is paramount. We offer Obeticholic Acid with detailed specifications and quality assurance, ensuring that it is suitable for demanding research applications. Our commitment as a global Obeticholic Acid supplier means we can support your projects from early-stage research to later development phases. We encourage inquiries for pricing and bulk purchases, aiming to provide accessible and high-quality pharmaceutical intermediates.
In essence, Obeticholic Acid (CAS 459789-99-2) is a vital compound for advancing our understanding and treatment of liver diseases. By focusing on FXR agonism, researchers can unlock new therapeutic strategies. We are dedicated to supporting this progress by being a trusted source for this essential research chemical.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
