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Obeticholic Acid (CAS 459789-99-2) is a synthetic bile acid analogue that acts as a potent and selective agonist for the Farnesoid X Receptor (FXR). This compound has gained considerable traction in pharmaceutical research due to its therapeutic potential in metabolic and liver diseases. Understanding its chemical properties and specific applications is crucial for researchers aiming to leverage its capabilities in drug discovery and development.
Chemically, Obeticholic Acid is characterized by its molecular formula C26H44O4 and a molecular weight of 420.634 g/mol. It typically presents as a white to off-white solid and exhibits solubility in DMSO and ethanol, though it is sparingly soluble in water. These properties are important considerations when preparing solutions for in vitro and in vivo experiments. As a reliable Obeticholic Acid supplier, we ensure that these chemical specifications are consistently met, providing researchers with a dependable product.
The primary research application of Obeticholic Acid centers around its potent FXR agonism. This interaction is fundamental to its role in regulating bile acid homeostasis, influencing hepatic and intestinal inflammation, and impacting liver fibrosis. In studies, Obeticholic Acid has been shown to effectively transactivate FXR, modulating the expression of key genes involved in these physiological processes. Researchers often seek to buy Obeticholic Acid to investigate its effects in models of cholestasis, NASH, and other liver-related pathologies.
Furthermore, Obeticholic Acid has demonstrated benefits in animal models, such as improving insulin sensitivity and reducing portal pressure in cirrhotic rats. Its utility extends to exploring its anticholeretic and anti-inflammatory actions. For scientists looking to purchase Obeticholic Acid, partnering with a reputable manufacturer ensures access to material of the required purity for accurate research outcomes. We are committed to being that trusted source, offering Obeticholic Acid with verified quality control data.
In summary, Obeticholic Acid (CAS 459789-99-2) is a vital research chemical with significant implications for understanding and treating a range of diseases. Its well-defined chemical properties and proven FXR agonism make it an indispensable tool in pharmaceutical research. We invite researchers to buy Obeticholic Acid from us, a dedicated supplier committed to supporting your scientific endeavors.
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A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
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