5-Methoxy-2-tetralone (CAS: 32940-15-1) stands as a pivotal chemical compound in the pharmaceutical industry, recognized for its crucial role as an intermediate in the synthesis of vital medications. With the chemical name 5-Methoxy-2-tetralone, this compound possesses a molecular formula of C11H12O2 and a molecular weight of 176.21. Typically appearing as a white to yellowish or light red solid, its physical characteristics underscore its stability and suitability for various chemical processes. NINGBO INNO PHARMCHEM CO.,LTD. is proud to offer this essential chemical with an impressive assay of 98% minimum, ensuring the high purity required for sensitive pharmaceutical applications.
The primary and most significant application of 5-Methoxy-2-tetralone is its indispensable use in the production of Rotigotine Hydrochloride. Rotigotine, a non-ergot dopamine receptor agonist, is a cornerstone in the treatment of Parkinson's disease. Notably, it gained prominence as the first transdermal patch drug for managing Parkinson's symptoms, offering a continuous and consistent therapeutic effect. The quality of 5-Methoxy-2-tetralone directly impacts the efficacy, safety, and overall integrity of the final Rotigotine Hydrochloride product. Therefore, securing a high-purity, reliable supply of this intermediate is paramount for pharmaceutical manufacturers globally.
In the past, the synthesis of 5-Methoxy-2-tetralone faced considerable challenges, often involving complex routes with low selectivity and difficult purification. Earlier methods might have utilized highly toxic substances, such as dimethyl sulfate, or hazardous metallic sodium, which presented significant safety concerns due to its reactivity with environmental humidity and explosive potential. Such traditional processes often led to costly raw materials, extended reaction times, and the generation of substantial waste pollutants.
NINGBO INNO PHARMCHEM CO.,LTD. has embraced and implemented advanced synthesis methodologies for 5-Methoxy-2-tetralone. Our contemporary approach focuses on overcoming these historical drawbacks by employing optimized reaction conditions, such as reducing 1,6-dimethoxynaphthalene in an alcohol and ammonia medium or synthesizing from 3-methoxyphenylacetic acid. These innovative techniques result in a manufacturing process characterized by mild reaction conditions, simplified operation, and the use of readily available, cost-effective raw materials. This commitment to modern synthesis ensures not only a high yield but also significantly reduces reaction steps and minimizes the generation of three-waste pollutants, aligning with global environmental and safety standards.
Our commitment to quality extends beyond just synthesis. NINGBO INNO PHARMCHEM CO.,LTD. maintains rigorous quality control procedures at every stage of production, from raw material inspection to final product analysis. Each batch of 5-Methoxy-2-tetralone undergoes comprehensive testing to verify its purity, appearance, and other critical specifications, guaranteeing that it consistently meets the demanding requirements of our pharmaceutical clients. We also ensure optimal packaging, typically in 25KG drums, and recommend appropriate storage conditions—such as a ventilated warehouse away from flames, high temperatures, oxidants, and acids—to preserve product integrity during transit and storage.
As a leading manufacturer and supplier of pharmaceutical intermediates, NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to fostering long-term partnerships with drug developers and pharmaceutical companies worldwide. Our reliable supply chain and efficient delivery times, typically within 7-10 days after payment, underscore our capability to meet urgent demands while maintaining the highest product standards. For inquiries regarding the price of 5-Methoxy-2-tetralone (CAS 32940-15-1), or to buy and purchase this critical pharmaceutical intermediate, we encourage prospective clients to contact our sales team. We are committed to providing competitive pricing and comprehensive support to facilitate your pharmaceutical research and production needs.
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