Beta Cyclodextrin, also known as Betadex, is a cyclic oligosaccharide composed of seven alpha-(1,4)-linked glucose units. This white, crystalline powder is highly regarded in the pharmaceutical industry and other sectors for its unique molecular structure and properties. The specific arrangement of glucose units forms a torus-shaped molecule with a hydrophobic internal cavity and a hydrophilic exterior. This characteristic structure allows Beta Cyclodextrin to encapsulate, or form inclusion complexes with, a wide range of non-polar or partially polar molecules, including many active pharmaceutical ingredients (APIs). The CAS number for Beta Cyclodextrin is 7585-39-9, a standard identifier for this essential compound.
The ability of Beta Cyclodextrin to form these inclusion complexes makes it an invaluable excipient in drug formulation. Many promising drug candidates suffer from poor water solubility, which significantly hinders their absorption and bioavailability in the body. By forming a complex with Beta Cyclodextrin, the apparent solubility and dissolution rate of these hydrophobic drugs in aqueous media can be dramatically increased. This solubilization effect is one of the primary reasons for its extensive use in various drug delivery systems, including oral, parenteral, and topical formulations.
Beyond solubility enhancement, Beta Cyclodextrin plays a crucial role in improving the stability of sensitive pharmaceutical compounds. Many drugs are susceptible to degradation via oxidation, hydrolysis, or photolysis when exposed to environmental factors like light, oxygen, or moisture. Encapsulating these drugs within the protective cavity of Beta Cyclodextrin shields them from these degradation pathways, thereby extending their shelf life and maintaining their potency over time. This stabilization effect is critical for ensuring the safety and efficacy of pharmaceutical products throughout their storage and distribution.
Furthermore, the use of Beta Cyclodextrin can lead to improved drug bioavailability. By enhancing solubility and dissolution, the drug becomes more readily available for absorption by the body. For drugs administered orally, this can mean faster onset of action and higher overall systemic exposure. In sustained-release formulations, Betadex can help control the release rate of the drug from the delivery system, leading to more consistent therapeutic levels in the bloodstream and potentially reducing dosing frequency. It acts effectively as a carrier material and sustained-release material in medicament applications.
Beta Cyclodextrin also offers advantages in improving the palatability and reducing irritation associated with certain drugs. Many APIs have a bitter taste or unpleasant odor that can make patient compliance difficult, especially in pediatric or geriatric populations. Forming a complex with Beta Cyclodextrin can effectively mask these undesirable sensory attributes. Similarly, for drugs that can cause local irritation at the site of administration, complexation can help mitigate these side effects, improving patient comfort and adherence.
For pharmaceutical applications, the quality and purity of Beta Cyclodextrin are paramount. High-grade Beta Cyclodextrin powder must meet stringent pharmacopoeial standards set by authoritative bodies such as the United States Pharmacopeia (USP), the British Pharmacopoeia (BP), the European Pharmacopoeia (EP), and the Chinese Pharmacopoeia (CP). Compliance with these standards ensures that the product is suitable for use in human medicine, free from harmful impurities, and exhibits consistent physical and chemical properties necessary for reliable formulation development and manufacturing. Key quality parameters typically assessed include assay content, moisture levels, purity profile, specific rotation, and absence of residual solvents.
As a dedicated *manufacturer* of high-quality pharmaceutical raw materials, NINGBO INNO PHARMCHEM CO.,LTD. is committed to producing Beta Cyclodextrin powder that fully complies with these international pharmacopoeial standards. Our manufacturing processes are meticulously controlled to ensure lot-to-lot consistency, purity, and reliability. We understand the critical importance of quality control in the pharmaceutical supply chain, and our product undergoes rigorous testing to verify its identity, purity, and performance characteristics, making it a reliable choice for pharmaceutical formulators worldwide.
The Beta Cyclodextrin powder is typically supplied in packaging designed to maintain its integrity and quality during transit and storage. Standard packaging often includes 25kg fiber drums, which provide robust protection. Proper storage conditions are essential; the product should be stored in a cool, dry place, preferably below 30 degrees Celsius, and protected against humidity and pressing. Following these storage guidelines ensures the product retains its quality and has a typical validity period of 2 years from the date of manufacture.
Choosing a reliable *supplier* for Beta Cyclodextrin is crucial for pharmaceutical companies. NINGBO INNO PHARMCHEM CO.,LTD. leverages extensive experience and technical expertise to provide a product that not only meets but often exceeds industry expectations. Our commitment to quality assurance is unwavering, ensuring that our Beta Cyclodextrin powder performs consistently in diverse pharmaceutical formulations, contributing to the development of safer and more effective medicines.
For companies looking to *buy* Beta Cyclodextrin or *purchase* Betadex in bulk, NINGBO INNO PHARMCHEM CO.,LTD. offers competitive solutions. We work closely with our clients to understand their specific needs and provide comprehensive support from inquiry through delivery. Our logistical capabilities ensure timely and secure shipments globally, simplifying the procurement process for our partners.
Inquiries regarding Beta Cyclodextrin *price*, technical specifications, samples, or lead times are always welcome. As a direct *manufacturer* and experienced *supplier*, we are positioned to offer favorable pricing structures based on order volume while maintaining the highest quality standards. Our goal is to be your trusted partner in sourcing premium pharmaceutical excipients.
In summary, high-quality Beta Cyclodextrin (Betadex) powder is an indispensable tool in modern pharmaceutical formulation. Its ability to improve drug solubility, stability, and bioavailability, along with other benefits like taste masking, makes it vital for developing patient-friendly and effective medications. NINGBO INNO PHARMCHEM CO.,LTD. is proud to be a leading *manufacturer* and *supplier* of this essential excipient, offering a product that meets global pharmacopoeial standards and supports innovation in the pharmaceutical industry. We invite potential clients to contact us to discuss their Beta Cyclodextrin requirements and experience the difference that quality and reliability can make in their projects. Whether you are seeking to *buy* a specific quantity or understand the Betadex *price* structure, our team is ready to assist you in making an informed *purchase* decision.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.