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NINGBO INNO PHARMCHEM CO.,LTD. is proud to supply Ibudilast powder, a multifaceted compound that serves as a powerful phosphodiesterase (PDE) inhibitor, offering significant therapeutic potential for both inflammatory and neurological disorders. This article delves into the compound's mechanism of action and its wide-ranging applications.
At its core, Ibudilast functions as a non-selective phosphodiesterase inhibitor. Phosphodiesterases are enzymes responsible for breaking down cyclic nucleotides, such as cyclic AMP (cAMP) and cyclic GMP (cGMP). By inhibiting these enzymes, Ibudilast leads to an increase in intracellular levels of cAMP, which in turn mediates a host of beneficial effects. A primary outcome of increased cAMP is the suppression of inflammatory pathways. This anti-inflammatory action is particularly effective in conditions like asthma and COPD, where inflammation of the airways is a major pathological feature. The investigation into Ibudilast for asthma and COPD is a testament to its efficacy in managing inflammatory respiratory conditions.
Beyond its role in inflammatory diseases, Ibudilast powder exhibits remarkable neuroprotective and anti-inflammatory properties within the central nervous system (CNS). It achieves this by inhibiting the activation of glial cells, such as microglia and astrocytes, which are key mediators of neuroinflammation. This action is critical for treating a range of neurological conditions, including multiple sclerosis (MS) and neuropathic pain. The extensive research on Ibudilast in multiple sclerosis treatment highlights its potential to slow disease progression and alleviate symptoms by reducing damaging neuroinflammation. Similarly, studies exploring Ibudilast for neuropathic pain show its promise in managing chronic pain conditions stemming from nerve damage.
For pharmaceutical companies looking to develop novel treatments for inflammatory and neurological conditions, sourcing high-quality Ibudilast powder is crucial. NINGBO INNO PHARMCHEM CO.,LTD. provides Ibudilast powder of exceptional purity, ensuring that your research and manufacturing processes benefit from a reliable and effective ingredient. We support your exploration of its capabilities, from understanding the nuances of immune modulation by Ibudilast to its potential in cytokine inhibition by Ibudilast.
The ongoing scientific inquiry into Ibudilast powder CAS 50847-11-5 continues to reveal its broad therapeutic spectrum. As a leading supplier of pharmaceutical raw materials, NINGBO INNO PHARMCHEM CO.,LTD. is committed to facilitating the development of groundbreaking therapies. Partner with us to access this vital compound and contribute to advancements in treating inflammatory diseases and neurological disorders worldwide.
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to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
