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The Neuroprotective Mechanisms of Ibudilast: Combating Neurodegeneration

NINGBO INNO PHARMCHEM CO.,LTD. is pleased to shed light on Ibudilast powder, a pharmaceutical compound increasingly recognized for its significant neuroprotective properties, which are crucial in the fight against neurodegenerative diseases. Understanding the intricate ways Ibudilast safeguards brain health is paramount for advancements in this critical therapeutic area.

Neurodegenerative diseases, such as Alzheimer's and Parkinson's, are characterized by the progressive loss of neuronal structure and function, often exacerbated by neuroinflammation and oxidative stress. Ibudilast powder acts as a potent inhibitor of phosphodiesterases, particularly PDE4, leading to an increase in intracellular cyclic AMP (cAMP) levels. This elevation of cAMP has a direct impact on reducing the activity of inflammatory cells in the brain, such as microglia and astrocytes. By suppressing these inflammatory responses, Ibudilast helps to create a more favorable environment for neuronal survival and function, thereby combating the neurodegenerative process. This mechanism is key to its potential in combating neurodegeneration.

The compound's ability to reduce oxidative stress, a major contributor to neuronal damage in many neurological conditions, further enhances its neuroprotective profile. Research highlights that Ibudilast can protect neurons from damage by lowering levels of damaging reactive oxygen species. This is vital for conditions where cellular integrity is compromised. Its demonstrated efficacy in preclinical models for conditions like Multiple Sclerosis (MS) and its investigation for use in Ibudilast for asthma and COPD illustrate its broad anti-inflammatory action, which is fundamentally beneficial for neurological health as well.

For pharmaceutical developers focused on neurological treatments, obtaining high-quality Ibudilast powder is a critical step. NINGBO INNO PHARMCHEM CO.,LTD. supplies Ibudilast powder that adheres to rigorous quality standards, ensuring consistency and efficacy in your research and product development. We support your efforts in exploring Ibudilast in multiple sclerosis treatment and its role in Ibudilast for neuropathic pain, recognizing the interconnectedness of inflammation and neurological disorders.

The continuous research into Ibudilast powder CAS 50847-11-5 is uncovering new therapeutic avenues. As a reliable source for this essential pharmaceutical intermediate, NINGBO INNO PHARMCHEM CO.,LTD. is committed to powering innovation in neuroprotection and disease management. Partner with us to harness the potential of Ibudilast powder and advance treatments for some of the most challenging neurological conditions facing society.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

FAQ

  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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NINGBO INNO PHARMCHEM CO.,LTD.
Address: No.163 Ruiqing Rd.,Ningbo 315000 China
Phone: 86-574-87319282
Fax: 86-574-27912196
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